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Purpose <p>To evaluate the long-term outcomes of primary filtering surgery, including trabeculectomy and combined trabeculotrabeculectomy (CTT), in secondary childhood glaucoma (SCG) patients.</p> Study design <p>Retrospective cohort study.</p> Methods <p>SCG patients, who underwent primary filtering surgery at two tertiary hospitals between 2008 and 2018, were reviewed. Surgical success was defined as an intraocular pressure (IOP) between 5 to 21&#xa0;mmHg. Failure was defined as IOP outside those criteria for two consecutive visits, the need for additional surgery, or loss of light perception. Surgical success was evaluated using the Kaplan–Meier method.</p> Results <p>Sixty-four eyes (50 patients) were included. Glaucoma associated with non-acquired ocular anomalies (SCG-O) included 31 eyes from 23 patients. Median age and follow-up time were 63.6 and 18&#xa0;months, respectively. Overall success probabilities were 57.8% at 1&#xa0;year, 55.1% at 3&#xa0;years, and 50.1% at 5&#xa0;years. For trabeculectomy (55 eyes), the success probabilities were 59.5% at 1 and 3&#xa0;years, and 52.0 % at 5&#xa0;years. For CTT (9 eyes), the success probabilities were 44.4% at 1&#xa0;year, decreasing to 33.3% at 3 and 5&#xa0;years. There was no statistically significant difference between trabeculectomy and CTT. Hypotony was the most common early complication. Two eyes developed phthisis bulbi.</p> Conclusions <p>Primary filtering surgery in SCG patients showed a significant drop in the success rate to about 60% within the first year, followed by a slight decline thereafter, with a long-term success rate around 50%.</p>

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Surgical outcomes of primary filtering surgery in secondary childhood glaucoma patients: a retrospective cohort study

  • 期刊论文

  • 发表日期：

    2025年7月26日

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  • Pukkapol Suvannachart,
  • Sunee Chansangpetch,
  • Supawan Surukrattanaskul,
  • Kitiya Ratanawongphaibul,
  • Anita Manassakorn,
  • Visanee Tantisevi,
  • Prin Rojanapongpun

摘要

Purpose

To evaluate the long-term outcomes of primary filtering surgery, including trabeculectomy and combined trabeculotrabeculectomy (CTT), in secondary childhood glaucoma (SCG) patients.

Study design

Retrospective cohort study.

Methods

SCG patients, who underwent primary filtering surgery at two tertiary hospitals between 2008 and 2018, were reviewed. Surgical success was defined as an intraocular pressure (IOP) between 5 to 21 mmHg. Failure was defined as IOP outside those criteria for two consecutive visits, the need for additional surgery, or loss of light perception. Surgical success was evaluated using the Kaplan–Meier method.

Results

Sixty-four eyes (50 patients) were included. Glaucoma associated with non-acquired ocular anomalies (SCG-O) included 31 eyes from 23 patients. Median age and follow-up time were 63.6 and 18 months, respectively. Overall success probabilities were 57.8% at 1 year, 55.1% at 3 years, and 50.1% at 5 years. For trabeculectomy (55 eyes), the success probabilities were 59.5% at 1 and 3 years, and 52.0 % at 5 years. For CTT (9 eyes), the success probabilities were 44.4% at 1 year, decreasing to 33.3% at 3 and 5 years. There was no statistically significant difference between trabeculectomy and CTT. Hypotony was the most common early complication. Two eyes developed phthisis bulbi.

Conclusions

Primary filtering surgery in SCG patients showed a significant drop in the success rate to about 60% within the first year, followed by a slight decline thereafter, with a long-term success rate around 50%.