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Datura Stramonium <p>L. (Solanaceae) is a&#xa0;wild plant native to Mexico. However, it has spread worldwide, including the Americas, Europe, Asia, Africa, and Oceania, due to its remarkable adaptability and invasive nature. The plant has been used for centuries in traditional medicine, especially for respiratory disorders, such as asthma. Despite its medicinal relevance, it is considered neurotoxic due to the presence of tropane alkaloids such as atropine, hyoscine, and scopolamine in different parts (especially in leaves and seeds) of the plant. All these alkaloids are associated with strong anticholinergic and psychoactive effects. Recent studies have shown the industrial and environmental relevance of this species, including applications in natural dye production, heavy-metal phytoremediation, corrosion inhibition, and nanomaterial synthesis. Therefore, this review article presents a&#xa0;holistic overview of the phytochemistry, pharmacological properties of <i>D.&#xa0;stramonium</i>, and highlights the industrial and environmental relevance of this species, which remains underexplored. Moreover, we also address the negative consequences associated with <i>D.&#xa0;stramonium</i>, focusing on human toxicity and poisoning incidents, misuse related to its hallucinogenic properties, and its invasive behaviour in non-native regions. Overall, this review provides a&#xa0;balanced assessment of both the beneficial and adverse aspects of <i>D.&#xa0;stramonium</i>, offering a&#xa0;comprehensive reference for future research and management strategies.</p>

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A Holistic Review of Jimson Weed (Datura Stramonium): Addressing Past Challenges and Future Advancements

  • 期刊论文

  • 发表日期：

    2026年8月4日

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  • Anita Sharma,
  • Shyna Bhalla,
  • Kritika Saini,
  • Parul Dhar,
  • Priyanka Mahajan

摘要

Datura Stramonium

L. (Solanaceae) is a wild plant native to Mexico. However, it has spread worldwide, including the Americas, Europe, Asia, Africa, and Oceania, due to its remarkable adaptability and invasive nature. The plant has been used for centuries in traditional medicine, especially for respiratory disorders, such as asthma. Despite its medicinal relevance, it is considered neurotoxic due to the presence of tropane alkaloids such as atropine, hyoscine, and scopolamine in different parts (especially in leaves and seeds) of the plant. All these alkaloids are associated with strong anticholinergic and psychoactive effects. Recent studies have shown the industrial and environmental relevance of this species, including applications in natural dye production, heavy-metal phytoremediation, corrosion inhibition, and nanomaterial synthesis. Therefore, this review article presents a holistic overview of the phytochemistry, pharmacological properties of D. stramonium, and highlights the industrial and environmental relevance of this species, which remains underexplored. Moreover, we also address the negative consequences associated with D. stramonium, focusing on human toxicity and poisoning incidents, misuse related to its hallucinogenic properties, and its invasive behaviour in non-native regions. Overall, this review provides a balanced assessment of both the beneficial and adverse aspects of D. stramonium, offering a comprehensive reference for future research and management strategies.