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Objective <p>Pulmonary MRI in neonates can be performed with quality comparable to radial 3D ultrashort echo time (UTE) MRI in significantly less time using a FLORET trajectory.</p> Materials and methods <p>Eighteen NICU patients with severe bronchopulmonary dysplasia (BPD), age 40.9 ± 3.0&#xa0;weeks at time of imaging, underwent MRI using Radial and FLORET UTE at 1.5&#xa0;T. Pulmonary signal-to-noise ratio (SNR), lung density, and radiologist scoring of motion artifacts and image quality were compared across sequence types.</p> Results <p>FLORET UTE reduced scan time by ~ 75% (4:40 vs. 16:41&#xa0;min.) while incurring only ~ 10–30% SNR reduction vs. radial (radial vs. 1-hub FLORET: 9.8 ± 2.8 vs. 9.0 ± 2.6, radial vs. 3-hub FLORET: 9.2 ± 3.0 vs. 7.7 ± 2.3), <i>P</i> &lt; 0.05. Normalized lung density measurements were elevated in FLORET (radial vs. 1-hub FLORET: 0.42 ± 0.13 vs. 0.49 ± 0.14, radial vs. 3-hub FLORET: 0.49 ± 0.13 vs. 0.51 ± 0.13), <i>P</i> &lt; 0.05. Accounting for scan time differences, normalized radial SNR was 19% and 16% lower than 1-hub and 3-hub FLORET, respectively (<i>P</i> &lt; 0.05). No significant differences in radiologist scores were found.</p> Conclusion <p>FLORET UTE images are of quality comparable to radial UTE at 75% of the total scan time, the current state of the art, and have a much greater time-SNR efficiency with enormous benefit in the neonatal population.</p>

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Reducing scan time burden for neonatal MRI of pulmonary structure using FLORET UTE

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月14日

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  • Andrew D. Hahn,
  • Matt M. Willmering,
  • Nara S. Higano,
  • Conner J. Wharff,
  • Robert J. Fleck,
  • Robert P. Guillerman,
  • Jason S. Woods,
  • Sean B. Fain

摘要

Objective

Pulmonary MRI in neonates can be performed with quality comparable to radial 3D ultrashort echo time (UTE) MRI in significantly less time using a FLORET trajectory.

Materials and methods

Eighteen NICU patients with severe bronchopulmonary dysplasia (BPD), age 40.9 ± 3.0 weeks at time of imaging, underwent MRI using Radial and FLORET UTE at 1.5 T. Pulmonary signal-to-noise ratio (SNR), lung density, and radiologist scoring of motion artifacts and image quality were compared across sequence types.

Results

FLORET UTE reduced scan time by ~ 75% (4:40 vs. 16:41 min.) while incurring only ~ 10–30% SNR reduction vs. radial (radial vs. 1-hub FLORET: 9.8 ± 2.8 vs. 9.0 ± 2.6, radial vs. 3-hub FLORET: 9.2 ± 3.0 vs. 7.7 ± 2.3), P < 0.05. Normalized lung density measurements were elevated in FLORET (radial vs. 1-hub FLORET: 0.42 ± 0.13 vs. 0.49 ± 0.14, radial vs. 3-hub FLORET: 0.49 ± 0.13 vs. 0.51 ± 0.13), P < 0.05. Accounting for scan time differences, normalized radial SNR was 19% and 16% lower than 1-hub and 3-hub FLORET, respectively (P < 0.05). No significant differences in radiologist scores were found.

Conclusion

FLORET UTE images are of quality comparable to radial UTE at 75% of the total scan time, the current state of the art, and have a much greater time-SNR efficiency with enormous benefit in the neonatal population.