Scholarlink

<p>This 78-year-old female patient presented to the outpatient department because of recent myoclonic and tonic-clonic seizures that had occurred more than 1&#xa0;year ago but did not relapse under newly instigated levetiracetam treatment, despite ongoing epileptiform discharges in the EEG. A routine electroencephalogram (EEG) during the outpatient examination confirmed the generalized spike and wave discharges typical for idiopathic generalized epilepsy. Due to this unexpected constellation an extensive survey of the medical history was undertaken revealing childhood absence epilepsy that had been treated with antiseizure medication until 12&#xa0;years of age. Since then the patient had remained seizure-free for 70&#xa0;years even without medication; however, several EEG updates during that time for different but not epilepsy-related reasons repeatedly confirmed generalized epileptiform EEG discharges with no seizure relapses. To our best knowledge this case demonstrates one of the longest seizure-free intervals in a&#xa0;case of idiopathic generalized epilepsy prior to a&#xa0;seizure relapse ever reported in the literature.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Anfallsrezidiv einer medikamentös unbehandelten idiopathisch generalisierten Epilepsie 60 Jahre nach klinisch abgeklungener kindlicher Absencenepilepsie

  • 期刊论文

  • 发表日期：

    2025年10月2日

查看全文
  • Bernhard J. Steinhoff,
  • Anke M. Staack

摘要

This 78-year-old female patient presented to the outpatient department because of recent myoclonic and tonic-clonic seizures that had occurred more than 1 year ago but did not relapse under newly instigated levetiracetam treatment, despite ongoing epileptiform discharges in the EEG. A routine electroencephalogram (EEG) during the outpatient examination confirmed the generalized spike and wave discharges typical for idiopathic generalized epilepsy. Due to this unexpected constellation an extensive survey of the medical history was undertaken revealing childhood absence epilepsy that had been treated with antiseizure medication until 12 years of age. Since then the patient had remained seizure-free for 70 years even without medication; however, several EEG updates during that time for different but not epilepsy-related reasons repeatedly confirmed generalized epileptiform EEG discharges with no seizure relapses. To our best knowledge this case demonstrates one of the longest seizure-free intervals in a case of idiopathic generalized epilepsy prior to a seizure relapse ever reported in the literature.