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<p>Transient dysfunction of cerebral structures relevant for memory with subsequent amnesia can sometimes be a&#xa0;manifestation of a&#xa0;particular form of epilepsy. This syndrome—called “transient <i>epileptic</i> amnesia” (TEA)—is not easily recognized, and relevant case series report a&#xa0;significant delay until a&#xa0;definite diagnosis is made. An initial misdiagnosis as transient <i>global </i>amnesia (TGA) could explain why some health insurance databases have found an association between TGA and incident epilepsy. This review explores potential explanations for this statistical observation and how it could impact our management of patients presenting with acute amnesia in the emergency department.</p>

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Transient global amnesia increases the risk of epilepsy: true or false?

  • 期刊论文

  • 发表日期：

    2025年3月23日

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  • Daniel Eschle

摘要

Transient dysfunction of cerebral structures relevant for memory with subsequent amnesia can sometimes be a manifestation of a particular form of epilepsy. This syndrome—called “transient epileptic amnesia” (TEA)—is not easily recognized, and relevant case series report a significant delay until a definite diagnosis is made. An initial misdiagnosis as transient global amnesia (TGA) could explain why some health insurance databases have found an association between TGA and incident epilepsy. This review explores potential explanations for this statistical observation and how it could impact our management of patients presenting with acute amnesia in the emergency department.