Hormonelle Kontrazeption bei arteriellem kardiovaskulärem Risiko
摘要
Arterial ischemic events are rare during the reproductive age; the risk of ischemic insult (approximately 10.7 per 100,000 woman-years) is higher than that of myocardial infarction (approximately 5.0 per 100,000 woman-years). The risk increases with age, particularly after 35 years. Major risk factors include arterial hypertension, diabetes, dyslipidemia, smoking, obesity and family history. Migraine with aura is an independent risk factor for an ischemic insult. Combined hormonal contraceptives double the risk of stroke and myocardial infarction, whereas levonorgestrel-releasing intrauterine devices (IUD) and Cu-IUDs are considered a safe alternative. Therefore, an individual risk assessment is recommended before prescribing hormonal contraception.