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<p>Endometriosis is a&#xa0;disease with a&#xa0;highly complex pathology. Characteristic features are infertility, chronic pain and a&#xa0;2–4-fold increased risk of ovarian cancer. The molecular pathology now recognizes somatic gene alterations that can potentially lead to endometriosis and also to a&#xa0;malignant transformation. Genomic alterations are suspected but currently are still speculative.</p>

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Endometriose und Karzinogenese

  • 期刊论文

  • 发表日期：

    2026年4月14日

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  • Wolfgang Küpker,
  • Ricardo E. Felberbaum,
  • Jörn Bullerdiek,
  • Jon Aizpurua,
  • Sylvia Mechsner,
  • Uwe Ulrich,
  • Klaus Diedrich

摘要

Endometriosis is a disease with a highly complex pathology. Characteristic features are infertility, chronic pain and a 2–4-fold increased risk of ovarian cancer. The molecular pathology now recognizes somatic gene alterations that can potentially lead to endometriosis and also to a malignant transformation. Genomic alterations are suspected but currently are still speculative.