Scholarlink

<p>Pre-operative planning for complex liver surgery is constrained by 2D CT/MRI. Digital 3D liver models (3DL-RL) may improve decision-making, but multicenter evidence on decision-level effects and inter-surgeon variability is limited. A multicenter, case-based survey was conducted among 10 HPB surgeons from all five Norwegian centers. Nine anonymized cases were reviewed in two phases: CT/MRI only, then CT/MRI + 3DL-RL. Fifty-five responses were collected to assess plans, usefulness, and adoption. Agreement and paired comparisons used Krippendorff’s <i>α</i>, Fleiss’ <i>κ</i>, Shapiro–Wilk, Levene’s, paired <i>t</i>, and Wilcoxon tests. 3DL-RL was associated with a significant planning shift (Wilcoxon <i>p</i> = 0.006, <i>r</i> = 0.372). Tumor counts changed in 41/55 (75%), always upward; plans changed in 64% of those versus 25% when counts were unchanged. Frequent modifications included parenchyma-sparing strategies 11/55 (20.0%), switch between surgery and another modality 6/55 (10.9%), extended resection 4/55 (7.3%), and refinements 8/55 (14.5%). Overall inter-surgeon agreement on binary planning remained low (Krippendorff’s <i>α</i> 0.207 CT/MRI vs 0.177 3DL-RL). Per-case anatomical agreement showed that <i>α</i> remains higher in the 3DL-RL group (0.664), with Cohen’s <i>d</i> = 0.571. Across Norwegian HPB units, 3DL-RL meaningfully influences pre-operative planning, often enabling parenchyma-sparing or other targeted changes, while serving as a complementary MDT aid. Variability persists across surgeons, consistent with individualized, precision-oriented decision-making. Larger, prospective, outcome-linked studies and ML-assisted workflows are needed to confirm clinical and economic impact.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The Clinical Utility of Three-Dimensional Liver Modelling: A Multicenter Survey

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月26日

查看全文
  • Keyur Radiya,
  • Eirik Kjus Aahlin,
  • Ashenafi Zebeneoldaregay,
  • Karl Øyvind Mikalsen,
  • Marjolein Henrieke Liedenbaum,
  • Gerit Pfuhl,
  • Kim Erlend Mortensen

摘要

Pre-operative planning for complex liver surgery is constrained by 2D CT/MRI. Digital 3D liver models (3DL-RL) may improve decision-making, but multicenter evidence on decision-level effects and inter-surgeon variability is limited. A multicenter, case-based survey was conducted among 10 HPB surgeons from all five Norwegian centers. Nine anonymized cases were reviewed in two phases: CT/MRI only, then CT/MRI + 3DL-RL. Fifty-five responses were collected to assess plans, usefulness, and adoption. Agreement and paired comparisons used Krippendorff’s α, Fleiss’ κ, Shapiro–Wilk, Levene’s, paired t, and Wilcoxon tests. 3DL-RL was associated with a significant planning shift (Wilcoxon p = 0.006, r = 0.372). Tumor counts changed in 41/55 (75%), always upward; plans changed in 64% of those versus 25% when counts were unchanged. Frequent modifications included parenchyma-sparing strategies 11/55 (20.0%), switch between surgery and another modality 6/55 (10.9%), extended resection 4/55 (7.3%), and refinements 8/55 (14.5%). Overall inter-surgeon agreement on binary planning remained low (Krippendorff’s α 0.207 CT/MRI vs 0.177 3DL-RL). Per-case anatomical agreement showed that α remains higher in the 3DL-RL group (0.664), with Cohen’s d = 0.571. Across Norwegian HPB units, 3DL-RL meaningfully influences pre-operative planning, often enabling parenchyma-sparing or other targeted changes, while serving as a complementary MDT aid. Variability persists across surgeons, consistent with individualized, precision-oriented decision-making. Larger, prospective, outcome-linked studies and ML-assisted workflows are needed to confirm clinical and economic impact.