Scholarlink

<p>De novo organogenesis is a key process in plant development and regeneration, enabling plants to adapt and survive under suboptimal conditions. Studying the molecular mechanisms of cellular reprogramming that drives new organ formation has been challenging since only a subset of cells among heterogeneous cell populations change the cell fate. Recent advancements in single-cell technologies, however, have begun to provide unprecedented insights into the cell identities and their developmental trajectories, offering a deeper understanding of cell fate transitions during this process. In this review we highlight how single-cell approaches help uncover the regulatory networks that govern cell fate reprogramming and propose future directions for improving temporal and spatial resolution to further advance this emerging field.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Single-cell views of fate reprogramming in de novo organogenesis

  • 期刊论文

  • 发表日期：

    2025年5月14日

查看全文
  • Hatsune Morinaka,
  • Yu Chen,
  • Keiko Sugimoto

摘要

De novo organogenesis is a key process in plant development and regeneration, enabling plants to adapt and survive under suboptimal conditions. Studying the molecular mechanisms of cellular reprogramming that drives new organ formation has been challenging since only a subset of cells among heterogeneous cell populations change the cell fate. Recent advancements in single-cell technologies, however, have begun to provide unprecedented insights into the cell identities and their developmental trajectories, offering a deeper understanding of cell fate transitions during this process. In this review we highlight how single-cell approaches help uncover the regulatory networks that govern cell fate reprogramming and propose future directions for improving temporal and spatial resolution to further advance this emerging field.