Scholarlink

<p>Magnetic resonance imaging derived proton density fat fraction (MRI-PDFF) is becoming increasingly important for assessing liver steatosis, which is traditionally diagnosed via liver biopsy. In the present study, we aimed to evaluate the efficacy of MRI-PDFF in detecting liver steatosis by comparing its values from various liver lobes—the right posterior hepatic lobe (RPHL), right anterior hepatic lobe (RAHL), left inner hepatic lobe (LIHL), left outer hepatic lobe (LOHL), the mean value of four hepatic lobes (M-PDFF), and the highest value of four hepatic lobes (H-PDFF)—against biopsy results. The findings indicated that MRI-PDFF exhibited strong performances in identifying liver steatosis in 125 patients, with area under the receiver operating characteristic (AUROC) values of 0.870 for RPHL, 0.875 for RAHL,&#xa0;0.881 for LIHL, 0.871 for LOHL, 0.881 for M-PDFF, and 0.878 for H-PDFF. Furthermore, MRI-PDFF demonstrated significant advantages in detecting moderate-to-severe steatosis, achieving AUROC values of 0.897 for RPHL, 0.911 for RAHL,&#xa0;0.905 for LIHL, 0.898 for LOHL, 0.907 for M-PDFF, and 0.904 for H-PDFF. Overall, MRI-PDFF is a highly accurate and noninvasive tool for diagnosing liver steatosis and determining its severity, making it valuable for clinical assessment and treatment.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The application performance of MRI-PDFF detection values of different hepatic lobes in diagnosing liver steatosis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年6月18日

查看全文
  • Fengjie Qiao,
  • Yan Xue,
  • Chen Zou,
  • Kun Liu,
  • Jie Yuan,
  • Longshan Ji,
  • Lingying Huang,
  • Man Li,
  • Yueqiu Gao

摘要

Magnetic resonance imaging derived proton density fat fraction (MRI-PDFF) is becoming increasingly important for assessing liver steatosis, which is traditionally diagnosed via liver biopsy. In the present study, we aimed to evaluate the efficacy of MRI-PDFF in detecting liver steatosis by comparing its values from various liver lobes—the right posterior hepatic lobe (RPHL), right anterior hepatic lobe (RAHL), left inner hepatic lobe (LIHL), left outer hepatic lobe (LOHL), the mean value of four hepatic lobes (M-PDFF), and the highest value of four hepatic lobes (H-PDFF)—against biopsy results. The findings indicated that MRI-PDFF exhibited strong performances in identifying liver steatosis in 125 patients, with area under the receiver operating characteristic (AUROC) values of 0.870 for RPHL, 0.875 for RAHL, 0.881 for LIHL, 0.871 for LOHL, 0.881 for M-PDFF, and 0.878 for H-PDFF. Furthermore, MRI-PDFF demonstrated significant advantages in detecting moderate-to-severe steatosis, achieving AUROC values of 0.897 for RPHL, 0.911 for RAHL, 0.905 for LIHL, 0.898 for LOHL, 0.907 for M-PDFF, and 0.904 for H-PDFF. Overall, MRI-PDFF is a highly accurate and noninvasive tool for diagnosing liver steatosis and determining its severity, making it valuable for clinical assessment and treatment.