Scholarlink

<p>This study aims to explore the impact of early mobilization on postoperative complications in adult patients after craniocerebral surgery. There is no meta-analysis study on early rehabilitation training in the prevention of postoperative complications of craniocerebral surgery yet. Patients after craniocerebral surgery often face various complications, including infection, hemorrhage and functional disorders, etc., which adversely affect their recovery quality. This study compared the effects of early activities (such as elevating the head of the bed, sitting up, standing, walking, etc.) within a defined postoperative time window, with traditional bed rest (full lying for ≥ 48&#xa0;h after surgery, with the head of the bed elevated ≤ 30°) on patient outcomes. A systematic literature search and screening of randomized controlled trials (RCTs) were performed. Quality assessment was conducted using the ROB2 tool. Data extraction and statistical analyses were carried out using R software and relevant statistical packages. The results showed that the pooled relative risk (RR) of postoperative complications in the early rehabilitation intervention group was 0.51 (95% confidence interval [CI]: 0.35–0.74; <i>P</i> = 0.0005), indicating a significant reduction in the incidence of postoperative complications with early mobilization. Sensitivity analyses demonstrated that excluding any single study did not alter the RR being less than 1 or the P value remaining below 0.05, thereby enhancing the robustness of the findings. The odds ratio (OR) for postoperative recurrence was 1.59 (95% CI: 0.53–4.79; <i>P</i> = 0.4119), and the OR for the Glasgow Outcome Scale-Extended (GOSE) score was 0.92 (95% CI: 0.51–1.63; <i>P</i> = 0.7683). Although the results for GOSE scores and postoperative recurrence rate after surgery was 1.59, the 95% confidence interval (CI) was [0.53,4.79], and <i>P</i> = 0.4119; The OR value of the GOSE score was 0.92, the 95%CI was [0.51,1.63], and <i>P</i> = 0.7683. Although the results of GOSE score and postoperative recurrence rate were not statistically significant, this study provides evidence supporting the safety of early rehabilitation interventions in reducing the risk of postoperative complications. Future research should prioritize high-quality trials to further investigate the potential impact of early mobilization on patient prognosis.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Effectiveness and safety of early rehabilitation in the prevention of postoperative complications after craniotomy: a systematic review and meta-analysis

  • 期刊论文

  • 发表日期：

    2026年1月10日

查看全文
  • Fan Li,
  • Jian Fei Han,
  • Qian Qian Zhang,
  • Leng Yue Zeng,
  • Hui Zhi Zhang

摘要

This study aims to explore the impact of early mobilization on postoperative complications in adult patients after craniocerebral surgery. There is no meta-analysis study on early rehabilitation training in the prevention of postoperative complications of craniocerebral surgery yet. Patients after craniocerebral surgery often face various complications, including infection, hemorrhage and functional disorders, etc., which adversely affect their recovery quality. This study compared the effects of early activities (such as elevating the head of the bed, sitting up, standing, walking, etc.) within a defined postoperative time window, with traditional bed rest (full lying for ≥ 48 h after surgery, with the head of the bed elevated ≤ 30°) on patient outcomes. A systematic literature search and screening of randomized controlled trials (RCTs) were performed. Quality assessment was conducted using the ROB2 tool. Data extraction and statistical analyses were carried out using R software and relevant statistical packages. The results showed that the pooled relative risk (RR) of postoperative complications in the early rehabilitation intervention group was 0.51 (95% confidence interval [CI]: 0.35–0.74; P = 0.0005), indicating a significant reduction in the incidence of postoperative complications with early mobilization. Sensitivity analyses demonstrated that excluding any single study did not alter the RR being less than 1 or the P value remaining below 0.05, thereby enhancing the robustness of the findings. The odds ratio (OR) for postoperative recurrence was 1.59 (95% CI: 0.53–4.79; P = 0.4119), and the OR for the Glasgow Outcome Scale-Extended (GOSE) score was 0.92 (95% CI: 0.51–1.63; P = 0.7683). Although the results for GOSE scores and postoperative recurrence rate after surgery was 1.59, the 95% confidence interval (CI) was [0.53,4.79], and P = 0.4119; The OR value of the GOSE score was 0.92, the 95%CI was [0.51,1.63], and P = 0.7683. Although the results of GOSE score and postoperative recurrence rate were not statistically significant, this study provides evidence supporting the safety of early rehabilitation interventions in reducing the risk of postoperative complications. Future research should prioritize high-quality trials to further investigate the potential impact of early mobilization on patient prognosis.