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<p>The management of small vestibular schwannomas (VS) with serviceable hearing remains controversial. While stereotactic radiosurgery (SRS) achieves high tumor control rates, its routine use for nongrowing, asymptomatic tumors may represent overtreatment. Decades of natural history data demonstrate that more than half of small or intracanalicular VSs remain radiographically stable for 10 years or longer, and many patients report high satisfaction with observation. Although SRS offers short-term hearing preservation, long-term outcomes show progressive decline, with fewer than half of patients maintaining serviceable hearing at five years and even fewer beyond a decade. Radiation also introduces potential late toxicities and complicates subsequent microsurgical salvage. Observation, by contrast, defers unnecessary intervention while preserving future treatment options and quality of life. For small, stable VSs, evidence supports a “wait-and-scan” strategy as the safest, most patient-centered initial management approach, reserving SRS or microsurgery for documented tumor progression or symptomatic deterioration. </p>

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Upfront radiation for small, nongrowing vestibular schwannomas: a call for caution

  • 期刊论文

  • 发表日期：

    2025年11月21日

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  • Nicholas S. Andresen,
  • Robert J. Macielak,
  • Desi P. Schoo,
  • Yin Ren,
  • Kyle C. Wu,
  • Daniel M. Prevedello,
  • Oliver F. Adunka,
  • William H. Saunders

摘要

The management of small vestibular schwannomas (VS) with serviceable hearing remains controversial. While stereotactic radiosurgery (SRS) achieves high tumor control rates, its routine use for nongrowing, asymptomatic tumors may represent overtreatment. Decades of natural history data demonstrate that more than half of small or intracanalicular VSs remain radiographically stable for 10 years or longer, and many patients report high satisfaction with observation. Although SRS offers short-term hearing preservation, long-term outcomes show progressive decline, with fewer than half of patients maintaining serviceable hearing at five years and even fewer beyond a decade. Radiation also introduces potential late toxicities and complicates subsequent microsurgical salvage. Observation, by contrast, defers unnecessary intervention while preserving future treatment options and quality of life. For small, stable VSs, evidence supports a “wait-and-scan” strategy as the safest, most patient-centered initial management approach, reserving SRS or microsurgery for documented tumor progression or symptomatic deterioration.