Scholarlink

<p>The term <i>early gastric cancer (EGC)</i>, defined as carcinoma confined to the mucosa or submucosa irrespective of lymph node status, has been widely accepted worldwide. In contrast, the terminology surrounding <i>advanced gastric cancer</i> remains inconsistent across regions. In Western oncology, “advanced cancer” often denotes unresectable or metastatic disease, whereas “early-stage cancer” may include resectable stage II–III tumors. This semantic discrepancy has led to confusion in international communication, clinical trials, and guideline interpretation. We propose a three-tier terminology—<i>early gastric cancer</i>, <i>locally advanced gastric cancer</i>, and <i>advanced gastric cancer</i>—to align the Japanese pathological concept with global clinical staging practice and therapeutic intent.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Reconsidering the terminology of “early” and “advanced” gastric cancer: toward a harmonized global lexicon

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月7日

查看全文
  • Takeshi Sano,
  • Narikazu Boku,
  • Florian Lordick

摘要

The term early gastric cancer (EGC), defined as carcinoma confined to the mucosa or submucosa irrespective of lymph node status, has been widely accepted worldwide. In contrast, the terminology surrounding advanced gastric cancer remains inconsistent across regions. In Western oncology, “advanced cancer” often denotes unresectable or metastatic disease, whereas “early-stage cancer” may include resectable stage II–III tumors. This semantic discrepancy has led to confusion in international communication, clinical trials, and guideline interpretation. We propose a three-tier terminology—early gastric cancer, locally advanced gastric cancer, and advanced gastric cancer—to align the Japanese pathological concept with global clinical staging practice and therapeutic intent.