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<p>Peritoneal metastasis (PM) is a major challenge in advanced gastric cancer (GC) with poor prognosis. Normothermic intraperitoneal and systemic treatment (NIPS) has become a promising therapeutic approach. This consensus aims to provide practical recommendations for NIPS treatment for gastric cancer with peritoneal metastasis (GCPM). The GRADE standards were used to rank evidence, and the Delphi method was employed for expert voting. 30 experts from China, Japan, South Korea, and Singapore participated in the development of this consensus. 28 experts participated in the voting process, which produced 29 statements covering diagnostic approaches, patient selection criteria, treatment regimens, management of intraperitoneal port placement, and conversion surgery considerations, and post-surgical treatment strategies in NIPS therapy. Based on current evidence and expert experience, these statements aim to improve the clinical outcomes of NIPS therapy for GCPM patients.</p>

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Asian consensus on normothermic intraperitoneal and systemic treatment for gastric cancer with peritoneal metastasis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月14日

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  • Zhenggang Zhu,
  • Joji Kitayama,
  • Hyung-Ho Kim,
  • Jimmy Bok-Yan So,
  • Hui Cao,
  • Lin Chen,
  • Xiangdong Cheng,
  • Jiankun Hu,
  • Motohiro Imano,
  • Hironori Ishigami,
  • Ye Seob Jee,
  • Jong-Han Kim,
  • Yasuhiro Kodera,
  • Han Liang,
  • Xiaowen Liu,
  • Sheng Lu,
  • Yiping Mou,
  • Mingming Nie,
  • Won Jun Seo,
  • Yanong Wang,
  • Dan Wu,
  • Zekuan Xu,
  • Hironori Yamaguchi,
  • Chao Yan,
  • Zhongyin Yang,
  • Kai Yin,
  • Yutaka Yonemura,
  • Wei-Peng Yong,
  • Jiren Yu,
  • Jun Zhang

摘要

Peritoneal metastasis (PM) is a major challenge in advanced gastric cancer (GC) with poor prognosis. Normothermic intraperitoneal and systemic treatment (NIPS) has become a promising therapeutic approach. This consensus aims to provide practical recommendations for NIPS treatment for gastric cancer with peritoneal metastasis (GCPM). The GRADE standards were used to rank evidence, and the Delphi method was employed for expert voting. 30 experts from China, Japan, South Korea, and Singapore participated in the development of this consensus. 28 experts participated in the voting process, which produced 29 statements covering diagnostic approaches, patient selection criteria, treatment regimens, management of intraperitoneal port placement, and conversion surgery considerations, and post-surgical treatment strategies in NIPS therapy. Based on current evidence and expert experience, these statements aim to improve the clinical outcomes of NIPS therapy for GCPM patients.