<p>In the context of increasing global displacement driven by conflicts and environmental factors, this systematic review explores the health challenges faced by adult migrants amidst climate change and multiple crises. Synthesizing qualitative studies, the research examines migrants’ perceptions of climate change and its impact on their health and well-being. While migration is often seen as an adaptation strategy to socio-environmental challenges, it also introduces significant stressors, such as cultural, linguistic, and economic barriers that hinder social integration. This review highlights the unique adaptive capacities of migrants, which can enhance both their resilience and that of host communities. It emphasizes the importance of participatory research in understanding the adaptive potential of migrants, as it provides valuable insights into their lived experiences and strategies for resilience. Such approaches can inform tailored adaptation strategies that address the specific experiences and needs of migrants, particularly in mental health, as they frequently endure emotional distress due to displacement and loss. The study advocates for a global, cooperative approach to tackle the interconnected challenges of migration and climate change, ensuring migrants receive adequate support to thrive in their new environments. By delving into the challenges migrants face regarding identity, belonging, and adapting to different cultural norms during crises, the review underscores the importance of interdisciplinary and context-sensitive approaches to develop effective policies and interventions. This comprehensive understanding of migrants’ experiences can lead to more effective adaptation and mitigation strategies, promoting holistic and sustainable solutions to this global issue.</p>