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Purpose <p>To illustrate the clinical use and feasibility of the REVEAL™ fluorescence loupe as an adjunctive tool in the chairside assessment of inflammatory, potentially malignant, and malignant oral lesions. </p> Methods <p>Five patients with oral lesions were clinically examined under natural light and with the REVEAL™ loupe. When indicated, biopsy and histopathological analysis were performed</p> Results <p>Inflammatory lesions exhibited a bright and homogeneous red autofluorescence pattern. Actinic cheilitis demonstrated heterogeneous brownish autofluorescence with whitish areas. Squamous cell carcinomas did not show significant autofluorescence contrast. The presence of biofilm was highlighted by a distinct orange signal.</p> Conclusion <p>The REVEAL™ loupe may support the clinical assessment of oral lesions by illustrating autofluorescence patterns associated with underlying tissue changes. However, its use should be considered complementary to biopsy, not a diagnostic substitute.</p>

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Clinical application of the REVEAL™ fluorescence loupe in oral lesion assessment: a five-case clinical note

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月23日

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  • Matheus Albino Souza,
  • Letícia Copatti Dogenski,
  • Gabriele Chitolina,
  • Eduarda Lunelli Ferrari,
  • Gisele Rovani,
  • Liviu Steier,
  • José Antônio Poli de Figueiredo,
  • João Paulo De Carli

摘要

Purpose

To illustrate the clinical use and feasibility of the REVEAL™ fluorescence loupe as an adjunctive tool in the chairside assessment of inflammatory, potentially malignant, and malignant oral lesions.

Methods

Five patients with oral lesions were clinically examined under natural light and with the REVEAL™ loupe. When indicated, biopsy and histopathological analysis were performed

Results

Inflammatory lesions exhibited a bright and homogeneous red autofluorescence pattern. Actinic cheilitis demonstrated heterogeneous brownish autofluorescence with whitish areas. Squamous cell carcinomas did not show significant autofluorescence contrast. The presence of biofilm was highlighted by a distinct orange signal.

Conclusion

The REVEAL™ loupe may support the clinical assessment of oral lesions by illustrating autofluorescence patterns associated with underlying tissue changes. However, its use should be considered complementary to biopsy, not a diagnostic substitute.