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<p>To explore the clinical efficacy and safety of long-pulse 1064nm Nd: YAG laser combined with pulsed CO2 laser and topical application of aminolevulinic acid hydrochloride for photodynamic therapy in treating pyogenic granuloma. 20 patients with pyogenic granuloma were treated with a combination of long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser along with photodynamic therapy using aminolevulinic acid hydrochloride. The efficacy, recurrence rate, and safety were observed at 1 month and 2 months post-treatment. All patients achieved a 100%cure rate and total effectiveness with a single treatment, with no infections, ulcers, or scars observed. Eight patients experienced mild pigmentation, which gradually resolved within one month, and there were no recurrences. The combined therapy of long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser with photodynamic therapy is highly effective in treating pyogenic granuloma, with no recurrences and minimal adverse reactions, significantly improving patient satisfaction.</p>

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Clinical observation of pyogenic granuloma treated with combined long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser photodynamic therapy

  • 期刊论文

  • 发表日期：

    2025年6月17日

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  • Xueyang Zhang,
  • Na Li,
  • Congmin Wang,
  • Junhong Ao,
  • Zhen Yuan,
  • Zixuan Qi,
  • Xiaomin Xu,
  • Aiqin Li,
  • Yujia Wang

摘要

To explore the clinical efficacy and safety of long-pulse 1064nm Nd: YAG laser combined with pulsed CO2 laser and topical application of aminolevulinic acid hydrochloride for photodynamic therapy in treating pyogenic granuloma. 20 patients with pyogenic granuloma were treated with a combination of long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser along with photodynamic therapy using aminolevulinic acid hydrochloride. The efficacy, recurrence rate, and safety were observed at 1 month and 2 months post-treatment. All patients achieved a 100%cure rate and total effectiveness with a single treatment, with no infections, ulcers, or scars observed. Eight patients experienced mild pigmentation, which gradually resolved within one month, and there were no recurrences. The combined therapy of long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser with photodynamic therapy is highly effective in treating pyogenic granuloma, with no recurrences and minimal adverse reactions, significantly improving patient satisfaction.