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Objective <p>High-intensity laser therapy (HILT) is a relatively new form of Nd: YAG laser. The aim of the study is to investigate the additional benefits of HILT with conventional physiotherapy, related to pain and function, in patients with knee osteoarthritis (KOA).</p> Method <p>The study comprised 43 knees from 31 patients of both genders with mean age 54.6 ± 6.22 (41–64) years. 53.49% of the knees were Kellgren Lawrence (KL) grade 2, and rest were KL grade 3 KOA. Group 1 (<i>n</i> = 21) received transcutaneous electrical nerve stimulation (TENS), hot packs (HP), exercises (EX), and HILT (Nd: yag-laser, 10&#xa0;W). Group 2 (<i>n</i> = 22), received the same interventions but placebo HILT. All interventions were applied for 10 sessions. The Visual Analog Scale (VAS), Western Ontario &amp; McMaster Universities Osteoarthritis Questionnaire (WOMAC), and Lequesne Algofunctional Index (LAI) were administered before, after, and at 12-week follow-up.</p> Results <p>Baseline VAS, WOMAC, and LAI scores of the groups were similar (<i>p</i> &gt; 0.05). After treatment and 12 weeks of follow-up, both groups had significant relief for VAS, WOMAC, LAI pain (respectively, <i>p</i> &lt; 0.001) and function (<i>p</i> &lt; 0.012), except LAI-walking distance (<i>p</i> = 0.415). Post-hoc analyses and mixed-effects models showed no significant differences between groups over time for all variables.</p> Conclusions <p>HILT did not provide additional short- or mid-term benefits in pain or function when added to a conventional physiotherapy and exercise program in patients with stage 2 or 3 knee osteoarthritis under 65 years of age.</p>

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Additional effect of high-intensity laser therapy with conventional physiotherapy related to pain and function in patients with knee osteoarthritis: a randomized, double-blind, placebo-controlled, 12-week follow-up study

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  • 发表日期：

    2025年6月7日

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  • Selen Özgözen,
  • Alaaddin Levent Özgözen,
  • Pınar Doruk Analan,
  • Caner İncekaş

摘要

Objective

High-intensity laser therapy (HILT) is a relatively new form of Nd: YAG laser. The aim of the study is to investigate the additional benefits of HILT with conventional physiotherapy, related to pain and function, in patients with knee osteoarthritis (KOA).

Method

The study comprised 43 knees from 31 patients of both genders with mean age 54.6 ± 6.22 (41–64) years. 53.49% of the knees were Kellgren Lawrence (KL) grade 2, and rest were KL grade 3 KOA. Group 1 (n = 21) received transcutaneous electrical nerve stimulation (TENS), hot packs (HP), exercises (EX), and HILT (Nd: yag-laser, 10 W). Group 2 (n = 22), received the same interventions but placebo HILT. All interventions were applied for 10 sessions. The Visual Analog Scale (VAS), Western Ontario & McMaster Universities Osteoarthritis Questionnaire (WOMAC), and Lequesne Algofunctional Index (LAI) were administered before, after, and at 12-week follow-up.

Results

Baseline VAS, WOMAC, and LAI scores of the groups were similar (p > 0.05). After treatment and 12 weeks of follow-up, both groups had significant relief for VAS, WOMAC, LAI pain (respectively, p < 0.001) and function (p < 0.012), except LAI-walking distance (p = 0.415). Post-hoc analyses and mixed-effects models showed no significant differences between groups over time for all variables.

Conclusions

HILT did not provide additional short- or mid-term benefits in pain or function when added to a conventional physiotherapy and exercise program in patients with stage 2 or 3 knee osteoarthritis under 65 years of age.