<p>Biohydrogen is a renewable energy source, limiting greenhouse gas emissions. Industrializing an efficient and economical process is a global priority. The objective of this study was to conduct an analysis and determine the most suitable reforming process for biohydrogen production. However, six reforming processes were evaluated using a combination of the Fuzzy TOPSIS multicriteria decision-making method and the entropy method for weighting criteria, taking into account technical, economic, and environmental criteria. For economic analysis, necessary calculations were conducted to define the fixed capital investment and fixed production costs of the six processes. The results of the comparison showed that steam reforming was ranked first, being the most suitable thermochemical process for cost-effective industrial biohydrogen production. Other processes, including dry reforming and partial oxidation, received low ratings and require further improvements before their industrialization. A parametric sensitivity analysis validated the robustness of the obtained results. Subsequently, the role of the steam reforming process in achieving the Sustainable Development Goals and its limitations were discussed. This study facilitates industrial decision making and ensures the choice of the most appropriate reforming process to produce biohydrogen from bio-oils, on an industrial scale.</p> Graphical Abstract <p></p>