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<p>The purpose was to validate the applicability of the Phoenix Sepsis Score and to compare it with other scores. The applicability of the Phoenix Sepsis Score in children with different primary statuses and age groups was compared. This study is a retrospective study. Children aged between 1 month and 18 years with a clinically suspected diagnosis of sepsis from January 2020 to December 2024 were selected for the study. Clinical data were collected and Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment, and Pediatric Logistic Organ Dysfunction Score-2 scores were calculated. The predictive values were assessed using the receiver operator characteristic curve. Compare the area under the curve of different receiver operator characteristic curves.&#xa0;A total of 341 children were included, of which 203 were Male, with a median age of 32 months. There were 103 children with primary diseases. Based on the Phoenix Sepsis Score, 174patients were diagnosed with sepsis. All three scores were significantly higher in the death group. The areas under the curve of the Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores for death in children with suspected sepsis were 0.874(0.834,0.907), 0.884(0.846,0.923) and 0.867(0.826,0.901), respectively. There were no statistically significant differences between the three scores in terms of predictive value. The area under the curve of Phoenix Sepsis Score for death in all age groups from 1 month to 11 years old were greater than 0.808(0.700,0.890). The areas under the curve of the Phoenix Sepsis Score for death in children with or without primary diseases were 0.790(0.699,0.864) and 0.894(0.839,0.949), respectively.&#xa0;The Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores had high predictive value for mortality in children with suspected sepsis. The Phoenix Sepsis Score had good predictive value in children at different primary states and different age. The predictive value of the Phoenix Sepsis Score was lower in children with primary disease.</p>

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Assessment of Phoenix sepsis score: characterization of a cohort of children of different primary statuses and ages, 2020–2024

  • 期刊论文

  • 发表日期：

    2025年9月15日

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  • Wanyu Jia,
  • Ruiyang Sun,
  • Jiapu Hou,
  • Zewen Ding,
  • Peng Li,
  • Chunlan Song

摘要

The purpose was to validate the applicability of the Phoenix Sepsis Score and to compare it with other scores. The applicability of the Phoenix Sepsis Score in children with different primary statuses and age groups was compared. This study is a retrospective study. Children aged between 1 month and 18 years with a clinically suspected diagnosis of sepsis from January 2020 to December 2024 were selected for the study. Clinical data were collected and Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment, and Pediatric Logistic Organ Dysfunction Score-2 scores were calculated. The predictive values were assessed using the receiver operator characteristic curve. Compare the area under the curve of different receiver operator characteristic curves. A total of 341 children were included, of which 203 were Male, with a median age of 32 months. There were 103 children with primary diseases. Based on the Phoenix Sepsis Score, 174patients were diagnosed with sepsis. All three scores were significantly higher in the death group. The areas under the curve of the Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores for death in children with suspected sepsis were 0.874(0.834,0.907), 0.884(0.846,0.923) and 0.867(0.826,0.901), respectively. There were no statistically significant differences between the three scores in terms of predictive value. The area under the curve of Phoenix Sepsis Score for death in all age groups from 1 month to 11 years old were greater than 0.808(0.700,0.890). The areas under the curve of the Phoenix Sepsis Score for death in children with or without primary diseases were 0.790(0.699,0.864) and 0.894(0.839,0.949), respectively. The Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores had high predictive value for mortality in children with suspected sepsis. The Phoenix Sepsis Score had good predictive value in children at different primary states and different age. The predictive value of the Phoenix Sepsis Score was lower in children with primary disease.