Scholarlink

Background <p>Stroke remains one of the leading causes of death and disability worldwide. This population-based study aimed to examine trends in hospitalization, care processes and outcome of ischemic stroke patients in the Veneto Region over a 25-year period.</p> Methods <p>We retrospectively analyzed hospital discharge records of Veneto population from 2000 to 2024, estimating hospitalization rates (HRs) for ischemic stroke, key care process indicators, and short-term mortality. Annual percentage changes were calculated to identify trends.</p> Results <p>Overall, 176,351 patients were discharged with a primary diagnosis of ischemic stroke, 84,515 were males (47.9%) and 91,836 were females (52.1%). From 2000 to 2024, the age-standardized HR declined from 172.1 to 96.0 per 100,000 inhabitants and 30-day mortality from 18.3% to 10.5%. The use of intravenous thrombolysis and mechanical thrombectomy increased markedly during the study period, reaching 21.1% and 10.0% in 2024, respectively. During the study period, a higher proportion of patients was admitted to neurology wards (from 37.6% to 68.9%) and to hospitals with a Stroke Unit (SU) (from 63.0% to 89.5%). The sex- and age-adjusted odds of 30-day mortality were lower after admission to neurology wards compared to other wards [OR 0.44 (95% CI: 0.43 to 0.46), <i>p</i> &lt; 0.001] and among those admitted to hospitals with a SU compared to those without [OR 0.83 (95% CI: 0.80 to 0.86), <i>p</i> &lt; 0.001].</p> Conclusion <p>From 2000 to 2024, the Veneto Region has experienced a significant reduction in HRs and mortality among patients with ischemic stroke, alongside improvements in admission settings and use of revascularization therapies.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Changing trends in epidemiology, care and outcome of ischemic stroke over 25 years: a large population-based study

  • 期刊论文

  • 发表日期：

    2026年4月15日

查看全文
  • Mario Saia,
  • Laura Salmaso,
  • Manuel Cappellari,
  • Giovanni Girardi,
  • Claudio Barbiellini Amidei,
  • Francesco Avossa,
  • Ugo Fedeli

摘要

Background

Stroke remains one of the leading causes of death and disability worldwide. This population-based study aimed to examine trends in hospitalization, care processes and outcome of ischemic stroke patients in the Veneto Region over a 25-year period.

Methods

We retrospectively analyzed hospital discharge records of Veneto population from 2000 to 2024, estimating hospitalization rates (HRs) for ischemic stroke, key care process indicators, and short-term mortality. Annual percentage changes were calculated to identify trends.

Results

Overall, 176,351 patients were discharged with a primary diagnosis of ischemic stroke, 84,515 were males (47.9%) and 91,836 were females (52.1%). From 2000 to 2024, the age-standardized HR declined from 172.1 to 96.0 per 100,000 inhabitants and 30-day mortality from 18.3% to 10.5%. The use of intravenous thrombolysis and mechanical thrombectomy increased markedly during the study period, reaching 21.1% and 10.0% in 2024, respectively. During the study period, a higher proportion of patients was admitted to neurology wards (from 37.6% to 68.9%) and to hospitals with a Stroke Unit (SU) (from 63.0% to 89.5%). The sex- and age-adjusted odds of 30-day mortality were lower after admission to neurology wards compared to other wards [OR 0.44 (95% CI: 0.43 to 0.46), p < 0.001] and among those admitted to hospitals with a SU compared to those without [OR 0.83 (95% CI: 0.80 to 0.86), p < 0.001].

Conclusion

From 2000 to 2024, the Veneto Region has experienced a significant reduction in HRs and mortality among patients with ischemic stroke, alongside improvements in admission settings and use of revascularization therapies.