Scholarlink

<p>IgG4-related disease (IgG4-RD) rarely involves the CNS parenchyma. We report a 44-year-old man with left facial numbness and seizures. MRI showed right frontal-parietal dural thickening and parenchymal edema. Biopsy revealed IgG4 + plasma cells (&gt; 50/HPF) with obliterative phlebitis, confirming IgG4-RD. This case highlights the need to consider IgG4-RD in meningo-parenchymal lesions mimicking tumors or infections. Glucocorticoids should be initiated promptly after histopathologic confirmation.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

NeuroImages: IgG4-related disease with meningeal and parenchymal involvement on MRI and histopathology

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月10日

查看全文
  • Lina Li,
  • Haibing Xiao

摘要

IgG4-related disease (IgG4-RD) rarely involves the CNS parenchyma. We report a 44-year-old man with left facial numbness and seizures. MRI showed right frontal-parietal dural thickening and parenchymal edema. Biopsy revealed IgG4 + plasma cells (> 50/HPF) with obliterative phlebitis, confirming IgG4-RD. This case highlights the need to consider IgG4-RD in meningo-parenchymal lesions mimicking tumors or infections. Glucocorticoids should be initiated promptly after histopathologic confirmation.