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<p>A 40-year-old man presented with acute urinary retention and bilateral lower limb weakness. MRI revealed a longitudinally extensive T2 hyperintense spinal cord lesion from C6 to T10, predominantly involving the gray matter (“H sign”). Brain MRI and CSF studies were unremarkable. Serum MOG-IgG was positive. The patient was treated with intravenous corticosteroids, with subsequent clinical and radiologic improvement. The imaging and clinical findings were consistent with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).</p>

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The “H sign” in MOGAD myelitis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年5月6日

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  • Santiago Aristizabal Ortiz,
  • Laura Andrea Campaña Perilla,
  • Angela Patricia Guarnizo Capera

摘要

A 40-year-old man presented with acute urinary retention and bilateral lower limb weakness. MRI revealed a longitudinally extensive T2 hyperintense spinal cord lesion from C6 to T10, predominantly involving the gray matter (“H sign”). Brain MRI and CSF studies were unremarkable. Serum MOG-IgG was positive. The patient was treated with intravenous corticosteroids, with subsequent clinical and radiologic improvement. The imaging and clinical findings were consistent with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).