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<p>Large granular lymphocytic leukemia (LGLL) is often associated with autoimmune diseases, with rheumatoid arthritis diagnosed in approximately one-third of the patients. Nevertheless, other rheumatologic conditions should also be considered. We describe a male patient in his 50&#xa0;s with a long-standing clinical history suggestive of palindromic rheumatism, who was diagnosed with LGLL leukemia during an evaluation for fever and neutropenia.</p>

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T-cell large granular lymphocytic leukemia associated with palindromic rheumatism: A case report

  • 期刊论文

  • 发表日期：

    2026年1月23日

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  • Anastasia Mocritcaia,
  • Andrea Rivero,
  • Beatriz Frade-Sosa,
  • Chafik Chacur,
  • Raimon Sanmartí

摘要

Large granular lymphocytic leukemia (LGLL) is often associated with autoimmune diseases, with rheumatoid arthritis diagnosed in approximately one-third of the patients. Nevertheless, other rheumatologic conditions should also be considered. We describe a male patient in his 50 s with a long-standing clinical history suggestive of palindromic rheumatism, who was diagnosed with LGLL leukemia during an evaluation for fever and neutropenia.