Scholarlink

<p>The prevalence of neurocognitive disorders, including dementia is increasing in ageing populations globally. Conventional pen-and-paper neuropsychological assessments like the Montreal Cognitive Assessment (MoCA) are limited by their inability to correlate clinical cognitive scores with real-world functional performance. Efficacious, more ecologically valid and less operator-dependent assessment tools are needed to identify at-risk persons for early intervention. Technology-based tools like virtual reality (VR) are increasingly applied in healthcare, such as a novel “Cognitive Assessment using VIrtual REality” (CAVIRE-2) software which has been developed to assess the six domains of cognition automatically in 10&#xa0;min. The study aimed to validate the CAVIRE-2 as a tool based on a matrix of scores and time to complete the 13 VR scenarios to discriminate persons who are cognitively healthy from those with MCI. Multi-ethnic Asian adults aged 55–84&#xa0;years were recruited at a public primary care clinic in Singapore. Both CAVIRE-2 and MoCA were administered to each participant independently. 280 participants completed the study, of which 244 were found to be cognitively normal and 36 were cognitively impaired by MoCA. CAVIRE-2 showed moderate concurrent and convergent validity with MoCA and MMSE respectively. CAVIRE-2 demonstrated good test–retest reliability with Intraclass Correlation Coefficient of 0.89 (95% CI = 0.85–0.92, <i>p</i> &lt; 0.001), and good internal consistency with Cronbach’s alpha = 0.87. CAVIRE-2 displayed good discriminative ability with area under curve (AUC) of 0.88 (95% CI = 0.81–0.95, <i>p</i> &lt; 0.001), and an optimal cut-off score of &lt; 1850 (88.9% sensitivity, 70.5% specificity, Youden’s = 0.59). CAVIRE-2 is potentially a valid and reliable assessment tool comparable to MoCA, which can distinguish cognitive status.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Validity and reliability of a virtual reality system as an assessment tool for cognitive impairment based on the six cognitive domains

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月16日

查看全文
  • Jeremy Wui Ming Pang,
  • Jie En Lim,
  • Eileen Yi Ling Koh,
  • Ngiap Chuan Tan

摘要

The prevalence of neurocognitive disorders, including dementia is increasing in ageing populations globally. Conventional pen-and-paper neuropsychological assessments like the Montreal Cognitive Assessment (MoCA) are limited by their inability to correlate clinical cognitive scores with real-world functional performance. Efficacious, more ecologically valid and less operator-dependent assessment tools are needed to identify at-risk persons for early intervention. Technology-based tools like virtual reality (VR) are increasingly applied in healthcare, such as a novel “Cognitive Assessment using VIrtual REality” (CAVIRE-2) software which has been developed to assess the six domains of cognition automatically in 10 min. The study aimed to validate the CAVIRE-2 as a tool based on a matrix of scores and time to complete the 13 VR scenarios to discriminate persons who are cognitively healthy from those with MCI. Multi-ethnic Asian adults aged 55–84 years were recruited at a public primary care clinic in Singapore. Both CAVIRE-2 and MoCA were administered to each participant independently. 280 participants completed the study, of which 244 were found to be cognitively normal and 36 were cognitively impaired by MoCA. CAVIRE-2 showed moderate concurrent and convergent validity with MoCA and MMSE respectively. CAVIRE-2 demonstrated good test–retest reliability with Intraclass Correlation Coefficient of 0.89 (95% CI = 0.85–0.92, p < 0.001), and good internal consistency with Cronbach’s alpha = 0.87. CAVIRE-2 displayed good discriminative ability with area under curve (AUC) of 0.88 (95% CI = 0.81–0.95, p < 0.001), and an optimal cut-off score of < 1850 (88.9% sensitivity, 70.5% specificity, Youden’s = 0.59). CAVIRE-2 is potentially a valid and reliable assessment tool comparable to MoCA, which can distinguish cognitive status.