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Objective <p>The aim of this clinical trial was to evaluate the effectiveness of Piano level laser therapy using Nd-YAG laser and intramuscular EGF injection in pain alleviation, function, and quality of life improvement in patients suffering from myogenic TMD.</p> Materials and methods <p>A randomized clinical trial was performed on 29 patients suffering from chronic painful myogenic TMD based on diagnostic criteria for temporomandibular disorders. Group I (<i>n</i> = 13patients) was treated using 1064&#xa0;nm Nd-YAG Laser (4 sessions once/week). Group II (<i>n</i> = 14 patients) was treated by intramuscular injection of EGF. Pain using numerical rating score, pain free opening and unassisted maximum opening were measured at baseline, 7,14,21 days, 1 and 3 months. Quality of life using OHIP-14 was assessed at baseline, 1 and 3 months.</p> Results <p>Results showed that there was a significant pain reduction (<i>P</i> <b>&lt; 0.000</b>) and increase in pain free opening (P <b>&lt; 0.0001</b>) in both test groups. However, only group I showed a significant increase in maximum opening (<i>P</i> = <b>0.007</b>). Quality of life significantly improved in both groups (<i>P</i> = <b>0.0001</b>). There was no significant difference between the two treatments in pain scores, pain free opening, maximum opening nor quality of life.</p> Conclusion <p>Both treatment modalities offered effective and cost-effective non- to minimally invasive treatment options for myogenic TMD with no side effects.</p> Clinical relevance <p>Myogenic TMD forms a public health issue and is a common musculoskeletal problem causing pain and disability. The proposal of effective, non-invasive, and affordable treatment options can help solve this issue.</p>

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Piano level laser therapy versus epidermal growth factor injection for painful myogenic temporomandibular disorder (a randomized clinical trial)

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月6日

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  • Passant Osama Qataya,
  • Azza Mohamed Zaki,
  • Fatma Amin,
  • Ahmed Swedan,
  • Hagar Elkafrawy

摘要

Objective

The aim of this clinical trial was to evaluate the effectiveness of Piano level laser therapy using Nd-YAG laser and intramuscular EGF injection in pain alleviation, function, and quality of life improvement in patients suffering from myogenic TMD.

Materials and methods

A randomized clinical trial was performed on 29 patients suffering from chronic painful myogenic TMD based on diagnostic criteria for temporomandibular disorders. Group I (n = 13patients) was treated using 1064 nm Nd-YAG Laser (4 sessions once/week). Group II (n = 14 patients) was treated by intramuscular injection of EGF. Pain using numerical rating score, pain free opening and unassisted maximum opening were measured at baseline, 7,14,21 days, 1 and 3 months. Quality of life using OHIP-14 was assessed at baseline, 1 and 3 months.

Results

Results showed that there was a significant pain reduction (P < 0.000) and increase in pain free opening (P < 0.0001) in both test groups. However, only group I showed a significant increase in maximum opening (P = 0.007). Quality of life significantly improved in both groups (P = 0.0001). There was no significant difference between the two treatments in pain scores, pain free opening, maximum opening nor quality of life.

Conclusion

Both treatment modalities offered effective and cost-effective non- to minimally invasive treatment options for myogenic TMD with no side effects.

Clinical relevance

Myogenic TMD forms a public health issue and is a common musculoskeletal problem causing pain and disability. The proposal of effective, non-invasive, and affordable treatment options can help solve this issue.