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<p>The use of contrast-enhanced ultrasound (CEUS) has greatly increased in the field of vascular imaging in recent years. Ultrasound contrast agents consist of stable gas-filled microbubbles that are administered intravenously and serve as strictly intravascular reflectors of ultrasound waves. Several studies have investigated the potential clinical use of CEUS in various vascular territories, particularly the carotid arteries, the abdominal aorta and the kidneys. In this review article, we discuss the clinical benefits of CEUS, which are based on the higher contrast of the vascular lumen and the high-resolution imaging of microvascular perfusion in real time.</p><p>In the carotid arteries CEUS not only allows better delineation of the vessel wall but also the assessment of the vasa vasorum and neovascularization in atherosclerotic plaques. This opens the possibility of better cardiovascular risk stratification through the detection of vulnerable atherosclerotic plaques.</p><p>The use of CEUS has also proven helpful in various diseases of the abdominal aorta, particularly in detecting endoleaks following endovascular aortic repair. Its applications range from the evaluation of tissue perfusion in native and transplanted kidneys to perfusion in skeletal muscle, which could be useful in patients with peripheral arterial occlusive disease.</p>

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Kontrastmittelgestützter Ultraschall in der Gefäßdiagnostik

  • 期刊论文

  • 发表日期：

    2026年4月22日

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  • Daniel Staub,
  • Markus Aschwanden

摘要

The use of contrast-enhanced ultrasound (CEUS) has greatly increased in the field of vascular imaging in recent years. Ultrasound contrast agents consist of stable gas-filled microbubbles that are administered intravenously and serve as strictly intravascular reflectors of ultrasound waves. Several studies have investigated the potential clinical use of CEUS in various vascular territories, particularly the carotid arteries, the abdominal aorta and the kidneys. In this review article, we discuss the clinical benefits of CEUS, which are based on the higher contrast of the vascular lumen and the high-resolution imaging of microvascular perfusion in real time.

In the carotid arteries CEUS not only allows better delineation of the vessel wall but also the assessment of the vasa vasorum and neovascularization in atherosclerotic plaques. This opens the possibility of better cardiovascular risk stratification through the detection of vulnerable atherosclerotic plaques.

The use of CEUS has also proven helpful in various diseases of the abdominal aorta, particularly in detecting endoleaks following endovascular aortic repair. Its applications range from the evaluation of tissue perfusion in native and transplanted kidneys to perfusion in skeletal muscle, which could be useful in patients with peripheral arterial occlusive disease.