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Background <p>18F-Fluorodeoxyglucose positron-emission tomography/computed tomography (FDG-PET/CT) plays a&#xa0;central role in the individualized treatment of classical Hodgkin lymphoma.</p> Objective <p>For risk stratification and treatment planning, PET-based staging is performed before the start of therapy. Treatment response monitoring during and/or after systemic therapy is also performed with PET/CT to adapt the treatment.</p> Results <p>This treatment—adapted to the individual risk profile and therapeutic response—enables high cure rates in patients with Hodgkin lymphoma while simultaneously limiting negative side effects of treatment.</p> Conclusion <p>New parameters such as the metabolic tumor volume promise further optimization of individualized treatment concepts adapted to the individual patients’ risks.</p>

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Individualisierte Therapie des klassischen Hodgkin-Lymphoms

  • 期刊论文

  • 发表日期：

    2026年4月6日

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  • Justin Ferdinandus,
  • Katrin S. Roth,
  • Markus Dietlein,
  • Carsten Kobe

摘要

Background

18F-Fluorodeoxyglucose positron-emission tomography/computed tomography (FDG-PET/CT) plays a central role in the individualized treatment of classical Hodgkin lymphoma.

Objective

For risk stratification and treatment planning, PET-based staging is performed before the start of therapy. Treatment response monitoring during and/or after systemic therapy is also performed with PET/CT to adapt the treatment.

Results

This treatment—adapted to the individual risk profile and therapeutic response—enables high cure rates in patients with Hodgkin lymphoma while simultaneously limiting negative side effects of treatment.

Conclusion

New parameters such as the metabolic tumor volume promise further optimization of individualized treatment concepts adapted to the individual patients’ risks.