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Background <p>Ovarian cancer is one of the most aggressive gynecological cancers and the fifth leading cause of cancer-related deaths among women in Germany. In recent years, access to guideline-based therapy has improved.</p> Objective <p>This fact sheet provides an overview of the epidemiology of ovarian cancer in Germany, focusing on incidence, survival by stage and age groups, and socioeconomic differences.</p> Materials and methods <p>The analysis is based on data from all German state cancer registries, as well as population data from the Federal Statistical Office and the World Health Organization mortality statistics. Primary diagnoses of the ovary, fallopian tubes, and peritoneum were included, and staging was performed according to the FIGO (Fédération Internationale de Gynécologie et d’Obstétrique) classification. Age-standardized incidence, mortality rate, and absolute and relative 5‑year survival were calculated. Socioeconomic differences were depicted using the German Index of Socioeconomic Deprivation.</p> Results <p>Between 2018 and 2022, an average of 8700 new cases per year were diagnosed (median age&#xa0;68). The age-standardized incidence was 12.8 per 100,000 women, and the relative 5‑year survival rate was 49.9%. Women from socioeconomically deprived regions had both a&#xa0;lower incidence and a&#xa0;lower survival probability. Particularly in the middle age groups (50–69&#xa0;years), there was a&#xa0;decline in incidence, mortality rate, and an increase in median survival in advanced stages.</p> Conclusion <p>The fact sheet highlights both current findings and long-term trends in ovarian cancer. Despite positive developments in terms of incidence and survival rates, late diagnosis and the associated high mortality remain central issues. Differences in age groups and spatial deprivation should be considered in further healthcare planning.</p>

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Faktenblatt: Epidemiologie des Ovarialkarzinoms in Deutschland

  • 期刊论文

  • 发表日期：

    2025年6月17日

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  • Annemarie Schultz,
  • Maren Pflüger,
  • Constanze Schneider,
  • Gerhard Gebauer,
  • Barbara Schmalfeldt,
  • Frederik Peters

摘要

Background

Ovarian cancer is one of the most aggressive gynecological cancers and the fifth leading cause of cancer-related deaths among women in Germany. In recent years, access to guideline-based therapy has improved.

Objective

This fact sheet provides an overview of the epidemiology of ovarian cancer in Germany, focusing on incidence, survival by stage and age groups, and socioeconomic differences.

Materials and methods

The analysis is based on data from all German state cancer registries, as well as population data from the Federal Statistical Office and the World Health Organization mortality statistics. Primary diagnoses of the ovary, fallopian tubes, and peritoneum were included, and staging was performed according to the FIGO (Fédération Internationale de Gynécologie et d’Obstétrique) classification. Age-standardized incidence, mortality rate, and absolute and relative 5‑year survival were calculated. Socioeconomic differences were depicted using the German Index of Socioeconomic Deprivation.

Results

Between 2018 and 2022, an average of 8700 new cases per year were diagnosed (median age 68). The age-standardized incidence was 12.8 per 100,000 women, and the relative 5‑year survival rate was 49.9%. Women from socioeconomically deprived regions had both a lower incidence and a lower survival probability. Particularly in the middle age groups (50–69 years), there was a decline in incidence, mortality rate, and an increase in median survival in advanced stages.

Conclusion

The fact sheet highlights both current findings and long-term trends in ovarian cancer. Despite positive developments in terms of incidence and survival rates, late diagnosis and the associated high mortality remain central issues. Differences in age groups and spatial deprivation should be considered in further healthcare planning.