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<p>A stroma a‑reactive invasion front area (SARIFA) is a&#xa0;new prognostic biomarker in carcinomas. Essentially, SARIFA describes the occurrence of direct contact between at least five tumor cells and adipocytes. This phenomenon is extremely easy and quick to identify, shows an extremely low interobserver variability, and does not require any additional staining as it can be identified on standard HE sections. The prognostic efficiency has now been demonstrated in gastric, colorectal, pancreatic, and prostate carcinoma.</p>

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SARIFA – ein neuer entitätenübergreifender Biomarker

  • 期刊论文

  • 发表日期：

    2025年2月5日

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  • Bianca Grosser,
  • Nic G. Reitsam,
  • Przmyslaw Grochowski,
  • Lukas Rentschler,
  • Johanna Enke,
  • Bruno Märkl

摘要

A stroma a‑reactive invasion front area (SARIFA) is a new prognostic biomarker in carcinomas. Essentially, SARIFA describes the occurrence of direct contact between at least five tumor cells and adipocytes. This phenomenon is extremely easy and quick to identify, shows an extremely low interobserver variability, and does not require any additional staining as it can be identified on standard HE sections. The prognostic efficiency has now been demonstrated in gastric, colorectal, pancreatic, and prostate carcinoma.