<p>This study examines the static flexural response of composite panel reinforced with graphene origami patterns under combined thermal and mechanical loadings. A kinematic framework incorporating shear deformation forms the basis for deriving the system's governing equations. These equations, expressing relationships between in-plane displacements and rotational degrees of freedom, are formulated using the virtual work principle. The associated boundary conditions are derived using the virtual work principle. Constitutive relations are established by determining the effective thermomechanical properties of the copper matrix composite containing graphene origami nanofillers, applying validated micromechanical methods. An analytical solution framework employing Navier's method is developed to solve the governing equations. Results detailing deformation, strain distributions and stress fields through the shell thickness are presented as functions of the foldability parameter. The main novelty of this work is investigating the stress, strain and deformation variations with changes of folding parameter along the thickness direction. Because of the simultaneous changes of the all materials properties and strain components, the stress variation needs a comprehensive investigation as presented in the paper. Analyses reveal that increasing the foldability parameter induces greater displacements and stresses. This trend is attributed to a corresponding reduction in the overall structural rigidity of the graphene origami reinforcement.</p>