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<p>The resurgence of monkey pox (mpox) virus clade Ib, which was declared a global health emergency in August 2024, poses a significant threat worldwide. Initially contained through public health measures, the increased transmissibility of clade Ib strains compared with that of previous strains has led to a rapid rise in cases, particularly in Central Africa. The resurgence highlights disparities in diagnostic capabilities and healthcare infrastructure, leading to underreporting in resource-limited regions. New variants could evade immunity, necessitating continued vaccination efforts for high-risk groups. This review discusses the epidemiological situation, recent outbreaks, clinical features, and public health response, emphasizing the urgent need for global coordination in diagnostic, prevention, and treatment strategies.</p>

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The resurgence of monkeypox clade Ib: a global health emergency and concern

  • 期刊论文

  • 发表日期：

    2025年3月21日

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  • Suresh Kumar,
  • Gunasekaran Subramaniam,
  • K. J. Senthil Kumar

摘要

The resurgence of monkey pox (mpox) virus clade Ib, which was declared a global health emergency in August 2024, poses a significant threat worldwide. Initially contained through public health measures, the increased transmissibility of clade Ib strains compared with that of previous strains has led to a rapid rise in cases, particularly in Central Africa. The resurgence highlights disparities in diagnostic capabilities and healthcare infrastructure, leading to underreporting in resource-limited regions. New variants could evade immunity, necessitating continued vaccination efforts for high-risk groups. This review discusses the epidemiological situation, recent outbreaks, clinical features, and public health response, emphasizing the urgent need for global coordination in diagnostic, prevention, and treatment strategies.