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<p>Parkinson’s disease (PD) is a progressive neurological disorder that significantly impacts quality of life. Over the past 25 years, deep brain stimulation (DBS) has emerged as an effective treatment option for individuals with advanced PD.. However, in India, DBS remains underutilized primarily due to financial constraints and a general lack of awareness, compounded by biases towards certain treatment centers. Additionally, the absence of definitive guidelines for implementing DBS in India further hampers its accessibility and adoption. Based on expert consensus, we propose a stepwise, five-point approach to optimize clinical outcomes for deep brain stimulation (DBS). This approach focuses on key areas including patient selection, indications for DBS in cases of medically refractory levodopa-induced motor complications or resistant tremor, and precise target selection. We emphasize the necessity of ensuring psychiatric stability and highlight the importance of a multidisciplinary approach, a comprehensive preoperative evaluation by multidisciplinary team of specialists including movement disorder experts, functional neurosurgeons etc critical for better, long-term outcomes. Furthermore, we recommend that DBS procedures be performed at specialized centers to ensure the highest standards of care and expertise.</p>

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Deep brain stimulation for Parkinson’s disease in India: an expert consensus on availability, affordability, and eligibility by the Parkinson’s research alliance India (PRAI)

  • 期刊论文

  • 发表日期：

    2026年2月3日

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  • Vinod Metta,
  • Rukmini Mridula,
  • Guruprasad Hosurkar,
  • Pettarusp Wadia,
  • Charulata Sankhla,
  • Pankaj Agarwal,
  • Sandeep Gurram,
  • Divyani Garg,
  • Sahil Mehta,
  • Hrishikesh Kumar,
  • Jacky Ganguly,
  • Roopa Rajan,
  • Arunmozhimaran Elavarasi,
  • Soaham Desai,
  • Lulup Kumar Sahoo,
  • Vijay Shankar,
  • Deepika Joshi,
  • Syam Krishnan,
  • Sruthi Kola,
  • Narendra Barad,
  • Vikram Holla,
  • Jacob Chacko,
  • Sampath Kumar,
  • Asha Kishore,
  • Prashanth L Kukkle,
  • Rajesh Alogolu,
  • Vinay Goyal,
  • K. Rajinder Dhamija,
  • Kallol Ray Chaudhuri,
  • Rupam Borgohain

摘要

Parkinson’s disease (PD) is a progressive neurological disorder that significantly impacts quality of life. Over the past 25 years, deep brain stimulation (DBS) has emerged as an effective treatment option for individuals with advanced PD.. However, in India, DBS remains underutilized primarily due to financial constraints and a general lack of awareness, compounded by biases towards certain treatment centers. Additionally, the absence of definitive guidelines for implementing DBS in India further hampers its accessibility and adoption. Based on expert consensus, we propose a stepwise, five-point approach to optimize clinical outcomes for deep brain stimulation (DBS). This approach focuses on key areas including patient selection, indications for DBS in cases of medically refractory levodopa-induced motor complications or resistant tremor, and precise target selection. We emphasize the necessity of ensuring psychiatric stability and highlight the importance of a multidisciplinary approach, a comprehensive preoperative evaluation by multidisciplinary team of specialists including movement disorder experts, functional neurosurgeons etc critical for better, long-term outcomes. Furthermore, we recommend that DBS procedures be performed at specialized centers to ensure the highest standards of care and expertise.