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<p>In Mexico City, a 49-year-old man underwent strangulation, which led to hypoxic-ischemic encephalopathy (HIE) and subsequently to delayed post-hypoxic leukoencephalopathy (DPHL), a rare demyelinating condition. Following the attack, he exhibited aphasia, dysphagia, and other neuropsychiatric symptoms that progressed to dementia. Imaging and brain biopsy analyses disclosed extensive ischemic damage and reactive gliosis. This case underscores the link between strangulation, acute HIE, and the subsequent development of DPHL, as well as an interpretation of the physiological implications of DPHL due to strangulation.</p>

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Chokehold with ‘rear naked choke’ and delayed post-hypoxic leukoencephalopathy: a new form of assault in Mexico City

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月19日

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  • Carlos Castillo-Rangel,
  • Cristofer Zarate-Calderon,
  • Carlos Castillo-Soriano,
  • Karla Aketzalli Hernández-Contreras,
  • Gerardo Marín-Márquez

摘要

In Mexico City, a 49-year-old man underwent strangulation, which led to hypoxic-ischemic encephalopathy (HIE) and subsequently to delayed post-hypoxic leukoencephalopathy (DPHL), a rare demyelinating condition. Following the attack, he exhibited aphasia, dysphagia, and other neuropsychiatric symptoms that progressed to dementia. Imaging and brain biopsy analyses disclosed extensive ischemic damage and reactive gliosis. This case underscores the link between strangulation, acute HIE, and the subsequent development of DPHL, as well as an interpretation of the physiological implications of DPHL due to strangulation.