Scholarlink

Objective <p>To explore the correlation between posterior fossa crowding and the occurrence of classical trigeminal neuralgia (TN).</p> Methods <p>A total of 60 patients diagnosed with classical TN and 60 age- and sex-matched healthy volunteers were included as a control group for a case-control study. All subjects underwent high-resolution 3D magnetic resonance imaging (MRI) examinations (including 3D-FIESTA and 3D-TOF MRA sequences). The original data were subjected to 3D reconstruction and measurement of posterior fossa volume (PFV) and hindbrain volume (HBV) using 3D-slicer software. The posterior fossa crowding index (PFCI) was calculated as HBV/PFV × 100%. Finally, data were analyzed using SPSS 22.0 statistical software.</p> Results <p>The average PFCI in patients with TN was 85.0% ± 3.9%, compared to 82.7% ± 3.9% in the control group, with a significant statistical difference (<i>P</i> = 0.025). Female patients with TN had a more crowded posterior fossa than male patients (86.4% ± 3.8% vs. 83.4% ± 3.4%, <i>P</i> = 0.033). Multiple linear regression analysis showed that a higher PFCI was associated with being female (<i>P</i> = 0.022), younger age (<i>P</i> = − 0.003), and being a patient with TN (<i>P</i> = − 0.023).</p> Conclusion <p>Patients with PTN have a more crowded posterior fossa compared to the healthy control group. A higher PFCI is associated with being female, younger age, and being a patient with TN. Posterior fossa crowding may be a risk factor for neurovascular conflict (NVC), making it more likely to lead to the occurrence of TN.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The correlation study between posterior fossa crowding and classical trigeminal neuralgia

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年1月14日

查看全文
  • Yinzhan Wang,
  • Yihui Du,
  • Wenchang Guo,
  • Yang Li,
  • Haowei Shi,
  • Zenghui Xi,
  • Tao Qian

摘要

Objective

To explore the correlation between posterior fossa crowding and the occurrence of classical trigeminal neuralgia (TN).

Methods

A total of 60 patients diagnosed with classical TN and 60 age- and sex-matched healthy volunteers were included as a control group for a case-control study. All subjects underwent high-resolution 3D magnetic resonance imaging (MRI) examinations (including 3D-FIESTA and 3D-TOF MRA sequences). The original data were subjected to 3D reconstruction and measurement of posterior fossa volume (PFV) and hindbrain volume (HBV) using 3D-slicer software. The posterior fossa crowding index (PFCI) was calculated as HBV/PFV × 100%. Finally, data were analyzed using SPSS 22.0 statistical software.

Results

The average PFCI in patients with TN was 85.0% ± 3.9%, compared to 82.7% ± 3.9% in the control group, with a significant statistical difference (P = 0.025). Female patients with TN had a more crowded posterior fossa than male patients (86.4% ± 3.8% vs. 83.4% ± 3.4%, P = 0.033). Multiple linear regression analysis showed that a higher PFCI was associated with being female (P = 0.022), younger age (P = − 0.003), and being a patient with TN (P = − 0.023).

Conclusion

Patients with PTN have a more crowded posterior fossa compared to the healthy control group. A higher PFCI is associated with being female, younger age, and being a patient with TN. Posterior fossa crowding may be a risk factor for neurovascular conflict (NVC), making it more likely to lead to the occurrence of TN.