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<p>Promoting human milk feeding is a&#xa0;cornerstone of medical therapy in neonatology. In premature and sick newborns, the use of human milk has been shown to reduce morbidity and mortality. If breastfeeding is not immediately possible, human milk banks provide donor milk as a&#xa0;transition to a&#xa0;mother’s own milk feeding. Human milk has a&#xa0;complex, individually varying composition that cannot be reproduced industrially. Preterm milk also contains a&#xa0;macro- and micronutrient composition adapted to the needs of preterm infants. However, due to the high demand for energy, protein, and minerals, fortification is necessary. In addition to standardized strategies, individualized approaches such as “targeted” and “adjustable fortification” are becoming increasingly important. Special techniques for modification (“lactoengineering”) or administration of human milk also enable nutrition tailored to personalized requirements. Interdisciplinary cooperation, especially with breastfeeding and lactation consultants and those responsible for human milk banks, is central to implementation. Further research into the future development of personalized and human milk-based nutrition concepts in neonatology is necessary.</p>

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Personalisierte und humanmilchbasierte Ernährungstherapie in der Neonatologie

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月8日

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  • Alexander Höller,
  • Claudia Peeters,
  • Monika Jörg-Streller,
  • Eva Huber,
  • Thomas Zöggeler,
  • Daniela Karall,
  • Anna Posod

摘要

Promoting human milk feeding is a cornerstone of medical therapy in neonatology. In premature and sick newborns, the use of human milk has been shown to reduce morbidity and mortality. If breastfeeding is not immediately possible, human milk banks provide donor milk as a transition to a mother’s own milk feeding. Human milk has a complex, individually varying composition that cannot be reproduced industrially. Preterm milk also contains a macro- and micronutrient composition adapted to the needs of preterm infants. However, due to the high demand for energy, protein, and minerals, fortification is necessary. In addition to standardized strategies, individualized approaches such as “targeted” and “adjustable fortification” are becoming increasingly important. Special techniques for modification (“lactoengineering”) or administration of human milk also enable nutrition tailored to personalized requirements. Interdisciplinary cooperation, especially with breastfeeding and lactation consultants and those responsible for human milk banks, is central to implementation. Further research into the future development of personalized and human milk-based nutrition concepts in neonatology is necessary.