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<p>Acetone in human exhaled breath is a key biomarker for diabetes, yet current metal oxide-based acetone sensors face challenges in detecting low-concentration acetone effectively at room temperature. Herein, we report a heterojunction by self-assembled peptide fibrillar nanoforests (SPNFs) and ZnO to fabricate an acetone sensor device. Among these materials, the well-ordered and uniformly arranged SPNFs offer a large surface area and a porous framework that promotes target gas adsorption, while also facilitating the homogeneous distribution of ZnO nanoparticles. Under room temperature and UV illumination, the SPNFs/ZnO-3 sensor demonstrates a response of 5.86 to 50 ppm acetone—over fourfold higher than that of pure ZnO. Furthermore, this sensor features a low detection limit and exhibits a response of 1.59 in the presence of 1 ppm acetone. The proposed methodology establishes a novel platform for the design and fabrication of gas sensors applicable to life health, environmental surveillance, and other fields, with excellent compatibility with existing microelectronic technology processes.</p> Graphical abstract <p></p>

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Room-temperature acetone sensing based on self-assembled peptide fibrillar nanoforests/ZnO under UV illumination

  • 期刊论文

  • 发表日期：

    2026年1月17日

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  • Yang Li,
  • Qingqun Lan,
  • Wei Wu,
  • Haisheng Li,
  • Yu Chen,
  • Yao Zan,
  • Wenxuan Hu,
  • Ranran Zhang

摘要

Acetone in human exhaled breath is a key biomarker for diabetes, yet current metal oxide-based acetone sensors face challenges in detecting low-concentration acetone effectively at room temperature. Herein, we report a heterojunction by self-assembled peptide fibrillar nanoforests (SPNFs) and ZnO to fabricate an acetone sensor device. Among these materials, the well-ordered and uniformly arranged SPNFs offer a large surface area and a porous framework that promotes target gas adsorption, while also facilitating the homogeneous distribution of ZnO nanoparticles. Under room temperature and UV illumination, the SPNFs/ZnO-3 sensor demonstrates a response of 5.86 to 50 ppm acetone—over fourfold higher than that of pure ZnO. Furthermore, this sensor features a low detection limit and exhibits a response of 1.59 in the presence of 1 ppm acetone. The proposed methodology establishes a novel platform for the design and fabrication of gas sensors applicable to life health, environmental surveillance, and other fields, with excellent compatibility with existing microelectronic technology processes.

Graphical abstract