<p>Efficient detection of plant viruses is an important link to ensure the safe production of crops. This research adopts MIL-101(Fe) metal organic framework materials as a molecularly imprinted matrix and tobacco mosaic virus (TMV) as a template molecule, successfully developing a visualized detection sensor with high selectivity. The sensor leverages three key mechanisms: (1) the porous structure of MIL-101(Fe) provides abundant binding sites, (2) framework Fe³⁺ ions coordinate with TMV capsid proteins for stable template fixation, and (3) zinc acrylate (Zn²⁺) introduces bimetallic synergy with Fe³⁺, enhancing recognition specificity. Experimental results show that the sensitivity of the sensor system for TMV detection reaches 13.2 fM, and it only takes 18&#xa0;min to complete the detection by naked eye. Compared with traditional detection methods, this technology gets rid of the reliance on high-cost biometric components (such as antibodies, nucleic acid probes), and the cost of a single detection is controlled at about 0.08 yuan. This simple and economical detection scheme provides a new technical means for monitoring plant viruses in the field and is of great significance for the prevention and control of crop diseases.</p> Graphical Abstract <p></p>