Scholarlink

<p>Metal–organic frameworks (MOFs) are often acted as potential candidates for the construction of efficient nanozymes due to their unique metal–ligand assembly structure, which can mimic different enzyme activities by modulating the metal nodes and ligand environment. In this study, a three-in-one composite metal–organic framework nanozymes (CeCu-MOFs) with excellent intrinsic peroxidase-like, oxidase-like, and catalase-like catalytic properties have been successfully prepared in environmentally friendly manner by a one-step chemical deposition method. Meanwhile, a catalytic platform for signal amplification was designed for quantitative measurement of ascorbic acid (AA) using the oxidase-like characteristic of CeCu-MOFs. The constructed colorimetric sensor achieved selective identification and accurate measurement of AA, demonstrated good linearity in the range 0.1–50&#xa0;μM with a detection limit of 0.063&#xa0;μM. We, further developed a portable smartphone-based platform for visual colorimetric determination of AA in real samples in point-of-care (POC) fashion by utilizing a portable paper-based device.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Smartphone-integrated colorimetric detection of ascorbic acid sensor based on CeCu-MOF nanozymes with enhanced triple-enzyme mimetic activity

  • 期刊论文

  • 发表日期：

    2025年8月11日

查看全文
  • Jianmei Chen,
  • Nengjing Zhou,
  • Xin Huang,
  • Zhongyu Sun,
  • Yongqi Ding

摘要

Metal–organic frameworks (MOFs) are often acted as potential candidates for the construction of efficient nanozymes due to their unique metal–ligand assembly structure, which can mimic different enzyme activities by modulating the metal nodes and ligand environment. In this study, a three-in-one composite metal–organic framework nanozymes (CeCu-MOFs) with excellent intrinsic peroxidase-like, oxidase-like, and catalase-like catalytic properties have been successfully prepared in environmentally friendly manner by a one-step chemical deposition method. Meanwhile, a catalytic platform for signal amplification was designed for quantitative measurement of ascorbic acid (AA) using the oxidase-like characteristic of CeCu-MOFs. The constructed colorimetric sensor achieved selective identification and accurate measurement of AA, demonstrated good linearity in the range 0.1–50 μM with a detection limit of 0.063 μM. We, further developed a portable smartphone-based platform for visual colorimetric determination of AA in real samples in point-of-care (POC) fashion by utilizing a portable paper-based device.

Graphical Abstract