<p>Roadway support presents a long-standing and complex challenge in underground engineering, especially within fractured rock masses, where it significantly influences both safety and sustainable development. The characteristics of complex fractured rock masses lie in the variability of their composition and structure, where significant differences in rock mass structure and quality classification may occur not only between different zones, but also within the same roadway segment. Consequently, identifying and delineating homogeneous domains within rock masses, followed by the implementation of targeted support designs for each domain, is crucial for addressing this challenge. This study proposes a method for the delineation of structural homogeneous domains and rock mass quality domains based on the spatial distribution characteristics of the blockiness (MBi) of fractured rock masses. A theoretical framework for the division of comprehensive homogeneous domains in complex fractured rock masses was established and applied in the engineering of surrounding rock in the Tongkeng mine. Based on the outcomes of the delineation of comprehensive homogeneous domains, a domain support design was developed. Furthermore, a comparative analysis was conducted between the proposed domain support scheme and the existing field support scheme in the study areas. The results indicate that the proposed support scheme effectively controls roof deformation, thereby significantly enhancing the stability of the surrounding rock.</p>