<p>Damage and fracture during rock creep have long been a focal point in rock mechanics research. To investigate the cross-scale damage and fracture behavior of pore-deficient sandstones, this study quantitatively assesses the creep fracture characteristics of various pore-deficient sandstones using fracture mechanics and the Digital Image Correlation (DIC) method. The creep damage characteristics are analyzed through the first law of thermodynamics and the Discrete Element Method (DEM). In addition, the microscopic mechanisms of creep damage in rocks are explored using crystal mechanics, Scanning Electron Microscope (SEM) tests, and machine learning techniques. This study also establishes the relationship between microscopic damage and macroscopic damage and fracture. The results reveal that the contribution of Mode I fracture to rock composite fracture decreases with increasing porosity. Creep damage predominantly occurs during the stable creep stage, with a higher porosity corresponding to a faster creep damage rate. Furthermore, the larger the exponent between the fractal dimension and the damage variable, the more pronounced the mineral dislocation fracture during rock damage. These findings provide valuable insights into the understanding of creep damage and fracture in rocks.</p>