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<p>Laparoscopic transabdominal preperitoneal repair (TAPP) is widely used for inguinal hernia repairs. Fibrin glue derived from allogeneic blood has been reported for mesh fixation, but there have been no reports on the use of autologous fibrin glue. Autologous fibrin glue (CryoSeal<sup>®</sup>) allows for full-surface mesh adhesion. We applied this technique in seven patients. Autologous blood was collected preoperatively and processed to prepare CryoSeal, which was sprayed over the mesh after standard TAPP placement. Three types of mesh were used, and the fixation was satisfactory in all cases. The median autologous blood and CryoSeal volumes were 200 mL and 15 mL, respectively, with median operative and spray times of 107&#xa0;min and 230&#xa0;s, respectively. Mesh fixation was achieved across the entire surface using a push test. No recurrence or postoperative complications were observed during the mean follow-up period of 170 days. This technique appears to be safe and clinically applicable for mesh fixation during inguinal hernia repair.</p>

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Autologous fibrin glue (CryoSeal®) for mesh fixation in laparoscopic transabdominal preperitoneal inguinal hernia repair: a how-to-do-it technique

  • 期刊论文

  • 发表日期：

    2026年7月31日

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  • Hiroyuki Hachiya,
  • Mitsuru Ishizuka,
  • Hikari Izumi,
  • Shotaro Miyashita,
  • Michi Ueno,
  • Takahiro Kono,
  • Masashi Takayanagi,
  • Tetsutaro Nemoto,
  • Norisuke Shibuya,
  • Keisuke Ihara,
  • Itaru Osaka,
  • Takatoshi Nakamura,
  • Tsunekazu Mizushima

摘要

Laparoscopic transabdominal preperitoneal repair (TAPP) is widely used for inguinal hernia repairs. Fibrin glue derived from allogeneic blood has been reported for mesh fixation, but there have been no reports on the use of autologous fibrin glue. Autologous fibrin glue (CryoSeal®) allows for full-surface mesh adhesion. We applied this technique in seven patients. Autologous blood was collected preoperatively and processed to prepare CryoSeal, which was sprayed over the mesh after standard TAPP placement. Three types of mesh were used, and the fixation was satisfactory in all cases. The median autologous blood and CryoSeal volumes were 200 mL and 15 mL, respectively, with median operative and spray times of 107 min and 230 s, respectively. Mesh fixation was achieved across the entire surface using a push test. No recurrence or postoperative complications were observed during the mean follow-up period of 170 days. This technique appears to be safe and clinically applicable for mesh fixation during inguinal hernia repair.