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Purpose <p>Urachal remnants are common in neonates and can persist into adulthood. However, their epidemiology in adults remains poorly characterized. We aimed to investigate the prevalence and clinical features of urachal remnants in adult Japanese patients with omphalitis using a nationwide claims database.</p> Methods <p>We analyzed data from the Japan Medical Data Center Claims Database (2005–2023) to identify patients  ≥ 15&#xa0;years of age who were diagnosed with omphalitis. The prevalence of urachal remnants, associated diagnoses, surgical interventions, and time to surgery was examined, focusing on sex differences and age distribution.</p> Results <p>Of the 11,477 patients with omphalitis, 1836 (16.0%) had urachal remnants, with a male-to-female ratio of 2.53:1. The prevalence peaked in males of 20–34&#xa0;years of age, exceeding 30%. Surgical intervention was performed in 39.7% of the cases, with a median time to surgery of 2&#xa0;months. The number of laparoscopic procedures increased after 2014 and surpassed that of open surgeries by 2018. One case of urachal cancer (0.054%) was also identified.</p> Conclusion <p>Urachal remnants are relatively common in adults with omphalitis, particularly in young males, and usually require surgery. Given the high prevalence and risk of recurrence, early imaging should be considered in adult omphalitis cases to support a timely diagnosis and intervention.</p>

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Epidemiology and treatment patterns of urachal remnants in adult patients with omphalitis: a nationwide claims-based study in Japan

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月15日

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  • Ryota Tokunaga,
  • Takenori Yamauchi,
  • Hiroki Den,
  • Shunsuke Omotaka,
  • Suguru Ogihara,
  • Masayuki Isozaki,
  • Takahiro Hobo,
  • Noboru Yokoyama,
  • Haruhiro Inoue,
  • Akatsuki Kokaze

摘要

Purpose

Urachal remnants are common in neonates and can persist into adulthood. However, their epidemiology in adults remains poorly characterized. We aimed to investigate the prevalence and clinical features of urachal remnants in adult Japanese patients with omphalitis using a nationwide claims database.

Methods

We analyzed data from the Japan Medical Data Center Claims Database (2005–2023) to identify patients  ≥ 15 years of age who were diagnosed with omphalitis. The prevalence of urachal remnants, associated diagnoses, surgical interventions, and time to surgery was examined, focusing on sex differences and age distribution.

Results

Of the 11,477 patients with omphalitis, 1836 (16.0%) had urachal remnants, with a male-to-female ratio of 2.53:1. The prevalence peaked in males of 20–34 years of age, exceeding 30%. Surgical intervention was performed in 39.7% of the cases, with a median time to surgery of 2 months. The number of laparoscopic procedures increased after 2014 and surpassed that of open surgeries by 2018. One case of urachal cancer (0.054%) was also identified.

Conclusion

Urachal remnants are relatively common in adults with omphalitis, particularly in young males, and usually require surgery. Given the high prevalence and risk of recurrence, early imaging should be considered in adult omphalitis cases to support a timely diagnosis and intervention.