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Purpose <p>The simple patch closure technique is an alternative method for repairing ventricular septal rupture following myocardial infarction. This single-center study aimed to investigate the outcomes of ventricular septal rupture repair.</p> Methods <p>This retrospective study included 23 patients who underwent initial surgery using the simple patch-closure technique between January 2009 and August 2024. Three primary endpoints were established: the rupture recurrence rate, in-hospital mortality rate, and mid-term survival rate. Survival curves were constructed using the Kaplan–Meier method.</p> Results <p>The mean patient age was 71.0&#xa0;years, and 13 patients were male. Intraoperative transesophageal echocardiography detected no residual shunts; however, five (21.7%) patients experienced rupture recurrence at a median of 21 (range, 12–150) days postoperatively, all requiring reoperation. The hospital mortality rate was 8.7%, with one death each in the early and late surgery groups. The 60&#xa0;month survival rate was 75.7% over a median follow-up period of 36&#xa0;months (range: 4–149&#xa0;months).</p> Conclusion <p>The simple patch closure technique is safe and effective for ventricular septal rupture repair, even in early surgery; however, recurrence remains a challenge. Preventive measures, such as bovine pericardial patches and the double-patch technique for extensive infarctions, warrant further validation through larger studies with longer follow-up periods.</p>

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Evaluating the efficacy of the simple patch closure technique in ventricular septal rupture repair following acute myocardial infarction: a retrospective single-center study

  • 期刊论文

  • 发表日期：

    2025年7月1日

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  • Ikuko Shibasaki,
  • Yasuyuki Yamada,
  • Shunsuke Saito,
  • Yusuke Takei,
  • Toshiyuki Kuwata,
  • Yuta Kanazaw,
  • Takashi Kato,
  • Go Tsuchiya,
  • Hironaga Ogawa,
  • Hirotsugu Fukuda

摘要

Purpose

The simple patch closure technique is an alternative method for repairing ventricular septal rupture following myocardial infarction. This single-center study aimed to investigate the outcomes of ventricular septal rupture repair.

Methods

This retrospective study included 23 patients who underwent initial surgery using the simple patch-closure technique between January 2009 and August 2024. Three primary endpoints were established: the rupture recurrence rate, in-hospital mortality rate, and mid-term survival rate. Survival curves were constructed using the Kaplan–Meier method.

Results

The mean patient age was 71.0 years, and 13 patients were male. Intraoperative transesophageal echocardiography detected no residual shunts; however, five (21.7%) patients experienced rupture recurrence at a median of 21 (range, 12–150) days postoperatively, all requiring reoperation. The hospital mortality rate was 8.7%, with one death each in the early and late surgery groups. The 60 month survival rate was 75.7% over a median follow-up period of 36 months (range: 4–149 months).

Conclusion

The simple patch closure technique is safe and effective for ventricular septal rupture repair, even in early surgery; however, recurrence remains a challenge. Preventive measures, such as bovine pericardial patches and the double-patch technique for extensive infarctions, warrant further validation through larger studies with longer follow-up periods.