Introduction <p>Lumbar fusion alters spinal biomechanics and may increase hip loading, especially with long-segment constructs. We used a large administrative database to evaluate hip fracture risk after lumbar fusion and assess whether fusion length influences this risk in younger and older adults.</p> Methods <p>Using PearlDiver, we identified patients ≥ 50 with lumbar degenerative disorders across three cohorts: nonoperative controls (<i>n</i> = 66,603), 1–6 level fusion (<i>n</i> = 44,402), and ≥ 7 level fusion (<i>n</i> = 22,201), matched by age and sex. Five-year hip fracture-free survival was estimated via Kaplan-Meier analysis, stratified by age (&lt; 65 vs. ≥ 65) and compared with log-rank tests.</p> Results <p>Hip fractures were uncommon across all groups (~ 1–2 per 1,000 person-years), with no significant overall differences between controls and fusion groups. In patients aged &lt; 65, long-segment fusion was associated with significantly lower hip fracture-free survival (χ²=22.11, <i>p</i> &lt; 0.00001) and a threefold higher hazard compared with short-segment fusion (HR 3.07, 95% CI 1.89–4.99; incidence 2.01 vs. 0.62 per 1,000 person-years). In patients ≥ 65, hip fracture rates were higher overall but did not differ significantly by fusion length (χ²=0.455, <i>p</i> = 0.50).</p> Conclusion <p>Lumbar fusion was associated with a small increase in hip fracture risk, with long constructs conferring substantially higher risk in adults &lt; 65.</p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Hip Fracture Risk Following Lumbar Fusion: A Retrospective Cohort Study of Construct Length and Age-Stratified Outcomes

  • James Anundson,
  • Linus Lee,
  • Sean Bae,
  • Joseph Ferguson,
  • Daniel Portney

摘要

Introduction

Lumbar fusion alters spinal biomechanics and may increase hip loading, especially with long-segment constructs. We used a large administrative database to evaluate hip fracture risk after lumbar fusion and assess whether fusion length influences this risk in younger and older adults.

Methods

Using PearlDiver, we identified patients ≥ 50 with lumbar degenerative disorders across three cohorts: nonoperative controls (n = 66,603), 1–6 level fusion (n = 44,402), and ≥ 7 level fusion (n = 22,201), matched by age and sex. Five-year hip fracture-free survival was estimated via Kaplan-Meier analysis, stratified by age (< 65 vs. ≥ 65) and compared with log-rank tests.

Results

Hip fractures were uncommon across all groups (~ 1–2 per 1,000 person-years), with no significant overall differences between controls and fusion groups. In patients aged < 65, long-segment fusion was associated with significantly lower hip fracture-free survival (χ²=22.11, p < 0.00001) and a threefold higher hazard compared with short-segment fusion (HR 3.07, 95% CI 1.89–4.99; incidence 2.01 vs. 0.62 per 1,000 person-years). In patients ≥ 65, hip fracture rates were higher overall but did not differ significantly by fusion length (χ²=0.455, p = 0.50).

Conclusion

Lumbar fusion was associated with a small increase in hip fracture risk, with long constructs conferring substantially higher risk in adults < 65.