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<p>Biosensors hold great promise for identifying and evaluating a wide range of abnormalities in the body of a human. Across the world, lung cancer stands as the leading cause of death among all cancers. It accounts for the highest number of cancer-related fatalities globally, underscoring its serious impact on public health and the urgent need for improved prevention, early detection, and treatment strategies. Noninvasive diagnosis has transformed the early identification of illnesses or anomalies in medicine by identifying specific biomarkers. The bloodless diagnostic is made using fluids in the body, including urine, saliva, sweat, and exhaled breath. An ideal diagnostic system consists of a unit for processing, data analysis software, sensors for identifying multiple volatile organic compounds (VOC), and an electronic circuit for extracting signals from the sensors. In non-invasive diagnostic studies, acetone (VOC) found in human breath-out has demonstrated great promise as a biomarker for early lung cancer and disease detection, providing a quick and easy screening method. In this work, the potential of glassy carbon (GC) electrode material with a TiO<InlineEquation ID="IEq1"> <EquationSource Format="TEX">\(_2\)</EquationSource> </InlineEquation>–ZnO–CNT sensing channel made with carbon microelectromechanical systems (C-MEMS) to sense acetone is explored. This strategy produced steady and dependable progress in the creation of reasonably priced, room-temperature biosensors for VOC detection.</p>

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Nanocomposite coated carbon-MEMS-derived glassy carbon electrode for acetone sensing

  • 期刊论文

  • 发表日期：

    2026年8月4日

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  • Anto Manuel,
  • S. Madhukumar,
  • Bidhan Pramanick

摘要

Biosensors hold great promise for identifying and evaluating a wide range of abnormalities in the body of a human. Across the world, lung cancer stands as the leading cause of death among all cancers. It accounts for the highest number of cancer-related fatalities globally, underscoring its serious impact on public health and the urgent need for improved prevention, early detection, and treatment strategies. Noninvasive diagnosis has transformed the early identification of illnesses or anomalies in medicine by identifying specific biomarkers. The bloodless diagnostic is made using fluids in the body, including urine, saliva, sweat, and exhaled breath. An ideal diagnostic system consists of a unit for processing, data analysis software, sensors for identifying multiple volatile organic compounds (VOC), and an electronic circuit for extracting signals from the sensors. In non-invasive diagnostic studies, acetone (VOC) found in human breath-out has demonstrated great promise as a biomarker for early lung cancer and disease detection, providing a quick and easy screening method. In this work, the potential of glassy carbon (GC) electrode material with a TiO \(_2\) –ZnO–CNT sensing channel made with carbon microelectromechanical systems (C-MEMS) to sense acetone is explored. This strategy produced steady and dependable progress in the creation of reasonably priced, room-temperature biosensors for VOC detection.