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<p>Opioid analgesics are powerful pain relievers, but inappropriate use can cause a variety of problems. Especially, in chronic non-cancer pain, inappropriate use of opioid analgesics might fail to improve or even worsen the quality of life and activities of daily living of patients impaired by pain. The Japan Society of Pain Clinicians has developed the Guidelines for Prescribing Opioid Analgesics for Chronic Non-cancer Pain (Third Edition), which answers basic clinical questions concerning opioid management as summary statements in accordance with&#xa0;the most recent scientific evidence and expert opinion. The guidelines emphasize patient selection (e.g., obvious organic cause of the persistent pain, low risk of psychosocial factors, pain refractory to non-opioid therapies, and good adherence to medication). Furthermore, patients should be treated with an oral dose of 90 morphine milligram equivalents/day as the upper limit and target duration of 3–6&#xa0;months. For pain in cancer survivors that is not directly caused by cancer, such as pain after treatment or pain associated with complications or pre-existing conditions, these guidelines should be followed.</p>

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Executive summary of the guideline for prescribing opioid analgesics for chronic non-cancer pain (third edition) by the Japan Society of Pain Clinicians

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月11日

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  • Akifumi Kanai,
  • Masako Iseki,
  • Hiroki Iida,
  • Shigeki Yamaguchi,
  • Ayano Oiwa,
  • Hiroshi Yonekura,
  • Narihito Iwashita,
  • Hiroshi Ueno,
  • Yoshiyuki Kimura,
  • Toshifumi Takasusuki,
  • Keisuke Yamaguchi,
  • Shie Iida,
  • Hiroko Ikemiya,
  • Rina Oya,
  • Yoko Sugiyama,
  • Kumiko Tanabe,
  • Ayano Taniguchi,
  • Yoshiyasu Hattammaru,
  • Maki Mizogami,
  • Shinobu Yamaguchi,
  • Keiko Yamada,
  • Sei Fukui

摘要

Opioid analgesics are powerful pain relievers, but inappropriate use can cause a variety of problems. Especially, in chronic non-cancer pain, inappropriate use of opioid analgesics might fail to improve or even worsen the quality of life and activities of daily living of patients impaired by pain. The Japan Society of Pain Clinicians has developed the Guidelines for Prescribing Opioid Analgesics for Chronic Non-cancer Pain (Third Edition), which answers basic clinical questions concerning opioid management as summary statements in accordance with the most recent scientific evidence and expert opinion. The guidelines emphasize patient selection (e.g., obvious organic cause of the persistent pain, low risk of psychosocial factors, pain refractory to non-opioid therapies, and good adherence to medication). Furthermore, patients should be treated with an oral dose of 90 morphine milligram equivalents/day as the upper limit and target duration of 3–6 months. For pain in cancer survivors that is not directly caused by cancer, such as pain after treatment or pain associated with complications or pre-existing conditions, these guidelines should be followed.