<p>Freezing of gait (FoG) refers to sudden, relatively brief episodes of gait arrest in Parkinson’s disease, known to manifest in the advanced stages of the condition. Events of freezing are associated with tumbles, traumas, and psychological repercussions, significantly impacting the patient’s quality of life. The use of accelerometer data derived from sensors put on a patient’s body to detect FoG has previously been proposed using convolutional neural network (CNN)-based deep learning algorithms. Here, we combine a CNN + Long short-term Memory (LSTM)-attention model to detect FoG episodes—a first for the detection of FoG using the accelerometer data. CNN facilitates automatic feature extraction from the accelerometer data itself. The output from the CNN is fed to the LSTM network, which is known for capturing sequential information. Further, the attention mechanism introduces relative focus on individual sub-sequences during the training of the LSTM network. The proposed model is made patient independent using adversarial training. The proposed model achieved improvements of +7.60% (without adversarial training) and + 8.36% (with adversarial training) in the sensitivity values over state of the art. This is obtained with little or no compromise in specificity values. The corresponding improvements in accuracy values are +3.81 and +2.23%, respectively. These findings imply that the proposed method can detect FoG gaits satisfactorily and can be effective in achieving accurate monitoring and gait assistance for Parkinson’s disease patients during daily life and rehabilitation therapy.</p>

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Enhancing patient-independent detection of freezing of gait in Parkinson’s disease with deep adversarial network

  • Md Shah Fahad,
  • Ashish Ranjan,
  • Gautam Kumar

摘要

Freezing of gait (FoG) refers to sudden, relatively brief episodes of gait arrest in Parkinson’s disease, known to manifest in the advanced stages of the condition. Events of freezing are associated with tumbles, traumas, and psychological repercussions, significantly impacting the patient’s quality of life. The use of accelerometer data derived from sensors put on a patient’s body to detect FoG has previously been proposed using convolutional neural network (CNN)-based deep learning algorithms. Here, we combine a CNN + Long short-term Memory (LSTM)-attention model to detect FoG episodes—a first for the detection of FoG using the accelerometer data. CNN facilitates automatic feature extraction from the accelerometer data itself. The output from the CNN is fed to the LSTM network, which is known for capturing sequential information. Further, the attention mechanism introduces relative focus on individual sub-sequences during the training of the LSTM network. The proposed model is made patient independent using adversarial training. The proposed model achieved improvements of +7.60% (without adversarial training) and + 8.36% (with adversarial training) in the sensitivity values over state of the art. This is obtained with little or no compromise in specificity values. The corresponding improvements in accuracy values are +3.81 and +2.23%, respectively. These findings imply that the proposed method can detect FoG gaits satisfactorily and can be effective in achieving accurate monitoring and gait assistance for Parkinson’s disease patients during daily life and rehabilitation therapy.