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Purpose <p>To identify dyadic patterns of family resilience among adolescents and young adults (AYAs) with cancer and their caregivers, and to explore associated factors and their relationships with quality of life (QoL) in both parties.</p> Methods <p>This cross-sectional study recruited 202 AYA patient-caregiver dyads from four tertiary hospitals in Wuhan and Taiyuan between July 2022 and March 2024. Data were collected through a self-designed general information questionnaire and validated instruments assessing family resilience, individual resilience, social support, and QoL. Family resilience clusters were identified using K-means clustering in R 4.4.3, followed by regression analyses in SPSS 20.0.</p> Results <p>Two family resilience clusters were identified: the low and high family resilience&#xa0;clusters. High resilience clusters were characterized by having an only child, a shorter disease course (1 ~ 3&#xa0;months), having a smaller family size (≤ 3 family members), and shorter daily caregiving hours. Caregiver QoL was associated with family resilience cluster, caregiver employment changes, and social support, whereas patient QoL was primarily influenced by their individual resilience.</p> Conclusions <p>This study identified heterogeneity in family resilience among AYA patient-caregiver dyads, with smaller family size, a shorter disease course, and shorter caregiving hours associated with membership in the high resilience cluster. Caregiver well-being was closely linked to family resilience and social-contextual factors, while patient QoL depended more on individual resilience. These findings advance understanding of family resilience in AYA oncology and underscore the importance of family-centered psychosocial support to strengthen family functioning, alleviate caregiver burden, and foster patient resilience.</p>

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Family resilience clusters and quality of life in adolescents and young adults with cancer and their caregivers: a dyadic cluster analysis

  • 期刊论文

  • 发表日期：

    2026年7月20日

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  • Yuxin Shen,
  • Hui Yang,
  • Yonghui Wan,
  • Shiguang Pang,
  • Lixiu Wang,
  • Mengying Hong,
  • Huijing Zou,
  • Dan Luo,
  • Xiao Qin Wang,
  • Bing Xiang Yang,
  • Qian Liu

摘要

Purpose

To identify dyadic patterns of family resilience among adolescents and young adults (AYAs) with cancer and their caregivers, and to explore associated factors and their relationships with quality of life (QoL) in both parties.

Methods

This cross-sectional study recruited 202 AYA patient-caregiver dyads from four tertiary hospitals in Wuhan and Taiyuan between July 2022 and March 2024. Data were collected through a self-designed general information questionnaire and validated instruments assessing family resilience, individual resilience, social support, and QoL. Family resilience clusters were identified using K-means clustering in R 4.4.3, followed by regression analyses in SPSS 20.0.

Results

Two family resilience clusters were identified: the low and high family resilience clusters. High resilience clusters were characterized by having an only child, a shorter disease course (1 ~ 3 months), having a smaller family size (≤ 3 family members), and shorter daily caregiving hours. Caregiver QoL was associated with family resilience cluster, caregiver employment changes, and social support, whereas patient QoL was primarily influenced by their individual resilience.

Conclusions

This study identified heterogeneity in family resilience among AYA patient-caregiver dyads, with smaller family size, a shorter disease course, and shorter caregiving hours associated with membership in the high resilience cluster. Caregiver well-being was closely linked to family resilience and social-contextual factors, while patient QoL depended more on individual resilience. These findings advance understanding of family resilience in AYA oncology and underscore the importance of family-centered psychosocial support to strengthen family functioning, alleviate caregiver burden, and foster patient resilience.