<p>Chemotherapy-induced nausea and vomiting (CINV) has been studied for decades, yet the overall scope and evolution of this literature have not been quantified. We conducted a cross-sectional survey of primary research articles on CINV published from database inception through January 2026, categorizing studies by chemotherapy emetogenicity. Nearly 3000 studies were identified, with publication output peaking in the 2010s and focusing predominantly on highly emetogenic regimens. These trends reflect historical clinical priorities and advances in antiemetic therapy.</p>

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Chemotherapy-induced nausea and vomiting in the literature: a cross-sectional analysis by time and emetogenicity

  • Ronald Chow,
  • Daniel Zhang,
  • Suhangi Brahmbhatt,
  • Jennifer Leigh,
  • Florian Scotté

摘要

Chemotherapy-induced nausea and vomiting (CINV) has been studied for decades, yet the overall scope and evolution of this literature have not been quantified. We conducted a cross-sectional survey of primary research articles on CINV published from database inception through January 2026, categorizing studies by chemotherapy emetogenicity. Nearly 3000 studies were identified, with publication output peaking in the 2010s and focusing predominantly on highly emetogenic regimens. These trends reflect historical clinical priorities and advances in antiemetic therapy.